News Column

Studies from Korea University Update Current Data on Viral RNA

May 27, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Viral RNA have been published. According to news originating from Seoul, South Korea, by NewsRx correspondents, research stated, "A mutant screening was carried out previously to look for new genes related to the Cucumber mosaic virus infection response in Arabidopsis. A Pumilio RNA binding protein-coding gene, Arabidopsis Pumilio RNA binding protein 5 (APUM5), was obtained from this screening."

Our news journalists obtained a quote from the research from Korea University, "APUM5 transcriptional profiling was carried out using a bioinformatics tool. We found that APUM5 was associated with both biotic and abiotic stress responses. However, bacterial and fungal pathogen infection susceptibility was not changed in APUM5 transgenic plants compared to that in wild type plants although APUM5 expression was induced upon pathogen infection. In contrast, APUM5 was involved in the abiotic stress response. 35S-APUM5 transgenic plants showed hypersensitive phenotypes under salt and drought stresses during germination, primary root elongation at the seedling stage, and at the vegetative stage in soil. We also showed that some abiotic stress-responsive genes were negatively regulated in 35S-APUM5 transgenic plants. The APUM5-Pumilio homology domain (PHD) protein bound to the 3' untranslated region (UTR) of the abiotic stress-responsive genes which contained putative Pumilio RNA binding motifs at the 3' UTR."

According to the news editors, the research concluded: "These results suggest that APUM5 may be a new post-transcriptional regulator of the abiotic stress response by direct binding of target genes 3' UTRs."

For more information on this research see: APUM5, encoding a Pumilio RNA binding protein, negatively regulates abiotic stress responsive gene expression. BMC Plant Biology, 2014;14():1-17. BMC Plant Biology can be contacted at: Biomed Central Ltd, 236 Grays Inn Rd, Floor 6, London WC1X 8HL, England. (BioMed Central - www.biomedcentral.com/; BMC Plant Biology - www.biomedcentral.com/bmcplantbiol/)

The news correspondents report that additional information may be obtained from S.U. Huh, Korea University, Coll Life Sci & Biotechnol, Seoul 136701, South Korea (see also Viral RNA).

Keywords for this news article include: Asia, Seoul, Viral RNA, South Korea, Nucleoproteins, Carrier Proteins, RNA-Binding Proteins

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Source: Life Science Weekly