News Column

Researchers from National Institutes of Health Report Recent Findings in Cancer Gene Therapy

May 26, 2014

By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- Current study results on Biotechnology have been published. According to news reporting originating from Research Triangle Park, North Carolina, by NewsRx correspondents, research stated, "Non-steroidal anti-inflammatory drugs (NSAIDs) are used extensively for analgesic and antipyretic treatments. In addition, NSAIDs reduce the risk and mortality to several cancers."

Our news editors obtained a quote from the research from the National Institutes of Health, "Their mechanisms in anti-tumorigenesis are not fully understood, but both cyclooxygenase (COX)-dependent and -independent pathways play a role. We and others have been interested in elucidating molecular targets of NSAID-induced apoptosis. In this review, we summarize updated literature regarding cellular and molecular targets modulated by NSAIDs."

According to the news editors, the research concluded: "Among those NSAIDs, sulindac sulfide and tolfenamic acid are emphasized in this review because these two drugs have been well investigated for their anti-tumorigenic activity in many different types of cancer."

For more information on this research see: Anti-tumor activity of non-steroidal anti-inflammatory drugs: Cyclooxygenase-independent targets. Cancer Letters, 2014;346(2):217-224. Cancer Letters can be contacted at: Elsevier Ireland Ltd, Elsevier House, Brookvale Plaza, East Park Shannon, Co, Clare, 00000, Ireland. (Elsevier -; Cancer Letters -

The news editors report that additional information may be obtained by contacting J.L. Liggett, NIEHS, Mol Carcinogenesis Lab, National Institutes of Health, Res Triangle Pk, NC 27709, United States. Additional authors for this research include X.B. Zhang, T.E. Eling and S.J. Baek (see also Biotechnology).

Keywords for this news article include: Biotechnology, Therapy, United States, North Carolina, Cyclooxygenase, Enzymes and Coenzymes, Research Triangle Park, North and Central America, Non-Steroidal Anti-Inflammatory Agents

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Cancer Gene Therapy Week

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