News Column

Research Conducted at Department of Pharmacy and Pharmacology Has Updated Our Knowledge about Chronic Pain

May 28, 2014



By a News Reporter-Staff News Editor at Biotech Week -- New research on Chronic Pain is the subject of a report. According to news reporting out of Johannesburg, South Africa, by NewsRx editors, research stated, "Chronic pain poses a major concern to modern medicine and is frequently undertreated, causing suffering and disability. Patient-controlled analgesia, although successful, does have limitations."

Our news journalists obtained a quote from the research from the Department of Pharmacy and Pharmacology, "Transdermal delivery is the pivot to which analgesic research in drug delivery has centralized, especially with the confines of needle phobias and associated pain related to traditional injections, and the existing limitations associated with oral drug delivery. Highlighted within is the possibility of further developing transdermal drug delivery for chronic pain treatment using iontophoresis-based microneedle array patches. A concerted effort was made to review critically all available therapies designed for the treatment of chronic pain. The drug delivery systems developed for this purpose and nondrug routes are elaborated on, in a systematic manner. Recent developments and future goals in transdermal delivery as a means to overcome the individual limitations of the aforementioned delivery routes are represented as well. The approval of patch-like devices that contain both the microelectronic-processing mechanism and the active medicament in a small portable device is still awaited by the pharmaceutical industry. This anticipated platform may provide transdermal electro-activated and electro-modulated drug delivery systems a feasible attempt in chronic pain treatment."

According to the news editors, the research concluded: "Iontophoresis has been proven an effective mode used to administer ionized drugs in physiotherapeutic, diagnostic, and dermatological applications and may be an encouraging probability for the development of devices and aids in the treatment of chronic pain."

For more information on this research see: Patient-controlled analgesia: therapeutic interventions using transdermal electro-activated and electro-modulated drug delivery. Journal of Pharmaceutical Sciences, 2014;103(2):353-66. (Wiley-Blackwell - www.wiley.com/; Journal of Pharmaceutical Sciences - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1520-6017)

Our news journalists report that additional information may be obtained by contacting S. Indermun, Dept. of Pharmacy and Pharmacology, Faculty of Health Sciences, University of the Witwatersr andParktown, Johannesburg, 2193, South Africa. Additional authors for this research include Y.E. Choonara, P. Kumar, L.C. Du Toit, G. Modi, R. Luttge and V. Pillay (see also Chronic Pain).

Keywords for this news article include: Therapy, Johannesburg, South Africa, Chronic Pain, Drug Delivery Systems.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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