News Column

New Magnetic Resonance Research Study Findings Have Been Reported by Researchers at University of Pennsylvania

May 27, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Magnetic Resonance Research. According to news reporting from Philadelphia, Pennsylvania, by NewsRx journalists, research stated, "High-resolution multi-dimensional solution NMR is unique as a biophysical and biochemical tool in its ability to examine both the structure and dynamics of macromolecules at atomic resolution. Conventional solution NMR approaches, however, are largely limited to examinations of relatively small (

The news correspondents obtained a quote from the research from the University of Pennsylvania, "Encapsulation of macromolecules within the protective nanoscale aqueous interior of reverse micelles dissolved in low viscosity fluids has been developed as a means through which the 'slow tumbling problem' can be overcome. This approach has been successfully applied to diverse proteins and nucleic acids ranging up to 100 kDa, considerably widening the range of biological macromolecules to which conventional solution NMR methodologies may be applied."

According to the news reporters, the research concluded: "Recent advances in methodology have significantly broadened the utility of this approach in structural biology and molecular biophysics."

For more information on this research see: High-resolution NMR spectroscopy of encapsulated proteins dissolved in low-viscosity fluids. Journal of Magnetic Resonance, 2014;241():137-147. Journal of Magnetic Resonance can be contacted at: Academic Press Inc Elsevier Science, 525 B St, Ste 1900, San Diego, CA 92101-4495, USA. (Elsevier -; Journal of Magnetic Resonance -

Our news journalists report that additional information may be obtained by contacting N.V. Nucci, University of Pennsylvania, Perelman Sch Med, Dept. of Biochem & Biophys, Johnson Res Fdn, Philadelphia, PA 19104, United States. Additional authors for this research include K.G. Valentine and A.J. Wand (see also Magnetic Resonance Research).

Keywords for this news article include: Peptides, Proteins, Amino Acids, Philadelphia, Pennsylvania, United States, North and Central America, Magnetic Resonance Research

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Source: Life Science Weekly

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