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Findings in Fibroblasts Reported from University of Putra Malaysia

May 27, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Fibroblasts have been presented. According to news reporting out of Selangor, Malaysia, by NewsRx editors, research stated, "Zn/Al-layered double hydroxide (LDH) was used as a host to intercalate various organic ultraviolet (UV) radiation absorbers. The intercalation compounds were prepared via the co-precipitation method."

Our news journalists obtained a quote from the research from the University of Putra Malaysia, "Powder X-ray diffraction (PXRD) confirmed the successful intercalation of anions into the interlayer regions of the LDH nanocomposites. As a result of intercalation, the resulting nanocomposites loaded with UV-ray absorbers, cinnamic acid (CA), benzophenone 4 (B4) and Eusolex (®)232 (EUS) exhibited basal spacings of 17.9 angstrom, 21.3 angstrom and 21.0 angstrom, respectively. Photochemical analysis revealed an increase in the UV-ray absorption capability of UV absorber/LDH nanocomposites compared to pure UV-ray absorbers. The retention ability of the organic moieties in the LDH host was tested in a skin pH simulation and was found to demonstrate low release over an extended period of time."

According to the news editors, the research concluded: "Cytotoxicity findings indicated that none of the nanocomposites exhibit significant cytotoxicity towards human dermal fibroblast (HDF) cells up to the test concentration of 25 mu g/mL."

For more information on this research see: Characterisation and Cytotoxicity Assessment of UV Absorbers-Intercalated Zinc/Aluminium-Layered Double Hydroxides on Dermal Fibroblast Cells. Science of Advanced Materials, 2014;6(4):648-658. Science of Advanced Materials can be contacted at: Amer Scientific Publishers, 26650 The Old Rd, Ste 208, Valencia, CA 91381-0751, USA. (American Scientific Publishers -

Our news journalists report that additional information may be obtained by contacting S.M.N. Mohsin, University of Putra Malaysia, Fac Sci, Catalysis Sci & Technol Res Center, Upm Serdang 43400, Selangor, Malaysia. Additional authors for this research include M.Z. Hussein, S.H. Sarijo, S. Fakurazi, P. Arulselvan and Y.H. Taufiq-Yap (see also Fibroblasts).

Keywords for this news article include: Asia, Anions, Selangor, Malaysia, Alkalies, Hydroxides, Fibroblasts, Nanocomposite, Nanotechnology, Inorganic Chemicals, Emerging Technologies, Connective Tissue Cells

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Source: Life Science Weekly

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