News Column

Findings from Seoul National University in the Area of Cancer Research Reported

May 27, 2014



By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators publish new report on Cancer Research. According to news reporting out of Seoul, South Korea, by NewsRx editors, research stated, "A human nose-mimetic diagnosis system that can distinguish the odor of a lung cancer biomarker, heptanal, from human blood is presented. Selective recognition of the biomarker is mimicked in the human olfactory system."

Our news journalists obtained a quote from the research from Seoul National University, "A specific olfactory receptor recognizing the chemical biomarker is first selected through screening a library of human olfactory receptors (hORs). The selected hOR is expressed on the membrane of human embryonic kidney (HEK)-293 cells. Nanovesicles containing the hOR on the membrane are produced from these cells, and are then used for the functionalization of single-walled carbon nanotubes. This strategy allows the development of a sensitive and selective nanovesicle-based bioelectronic nose (NvBN). The NvBN is able to selectively detect heptanal at a concentration as low as 1 x 10(-14) m, a sufficient level to distinguish the blood of a lung cancer patient from the blood of a healthy person. In actual experiments, NvBN could detect an extremely small increase in the amount of heptanal from human blood plasma without any pretreatment processes."

According to the news editors, the research concluded: "This result offers a rapid and easy method to analyze chemical biomarkers from human blood in real-time and to diagnose lung cancer."

For more information on this research see: Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Advanced Healthcare Materials, 2014;3(3):360-6. (Wiley-Blackwell - www.wiley.com/; Advanced Healthcare Materials - onlinelibrary.wiley.com/journal/10.1002/(ISSN)2192-2659)

Our news journalists report that additional information may be obtained by contacting J.H. Lim, School of Chemical and Biological Engineering, Bio-MAX Institute, Seoul National University, Seoul, 151-742, South Korea. Additional authors for this research include J. Park, E.H. Oh, H.J. Ko, S. Hong and T.H Park (see also Cancer Research).

Keywords for this news article include: Asia, Seoul, Oncology, South Korea, Cancer Research.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Cancer Weekly


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