News Column

Researchers from Murdoch University Detail Findings in Science

May 23, 2014

By a News Reporter-Staff News Editor at Science Letter -- Data detailed on Science have been presented. According to news reporting originating from Murdoch, Australia, by NewsRx correspondents, research stated, "In this preliminary study we investigate for the first time the biomedical potential of using porous anodic aluminium oxide (AAO) membranes as a cell substrate for culturing the Cercopithecus aethiops (African green monkey) Kidney (Vero) epithelial cell line. One advantage of using the inorganic AAO membrane is the presence of nanometre scale pore channels that allow the exchange of molecules and nutrients across the membrane."

Our news editors obtained a quote from the research from Murdoch University, "The size of the pore channels can be preselected by adjusting the controlling parameters of a temperature controlled two-step anodization process. The cellular interaction and response of the Vero cell line with an in-house synthesised AAO membrane, a commercially available membrane, and a glass control were assessed by investigating cell adhesion, morphology, and proliferation over a 72?h period. The number of viable cells proliferating over the respective membrane surfaces revealed that the locally produced in-house AAO membrane had cells numbers similar to the glass control. The study revealed evidence of focal adhesion sites over the surface of the nanoporous membranes and the penetration of cellular extensions into the pore structure as well."

According to the news editors, the research concluded: "The outcome of the study has revealed that nanometre scale porous AAO membranes have the potential to become practical cell culture scaffold substrates with the capability to enhance adhesion and proliferation of Vero cells."

For more information on this research see: Chemical synthesis, characterisation, and biocompatibility of nanometre scale porous anodic aluminium oxide membranes for use as a cell culture substrate for the vero cell line: a preliminary study. Biomed Research International, 2014;2014():238762 (see also Science).

The news editors report that additional information may be obtained by contacting G.E. Poinern, Murdoch Applied Nanotechnology Research Group, Dept. of Physics, Energy Studies and Nanotechnology, School of Engineering and Energy, Murdoch University, Murdoch, WA 6150, Australia. Additional authors for this research include X.T. Le, M. O'Dea, T. Becker and D. Fawcett.

Keywords for this news article include: Murdoch, Science, Chemicals, Chemistry, Aluminium Oxide, Australia and New Zealand.

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Source: Science Letter

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