News Column

Reports on DNA Research from Cavendish Laboratory Provide New Insights

May 23, 2014

By a News Reporter-Staff News Editor at Science Letter -- Current study results on DNA Research have been published. According to news originating from Cambridge, United Kingdom, by NewsRx correspondents, research stated, "Plasmonic sensors are extremely promising candidates for label-free single-molecule analysis but require exquisite control over the physical arrangement of metallic nanostructures. Here we employ self-assembly based on the DNA origami technique for accurate positioning of individual gold nanoparticles."

Our news journalists obtained a quote from the research from Cavendish Laboratory, "Our innovative design leads to strong plasmonic coupling between two 40 nm gold nanoparticles reproducibly held with gaps of 3.3 ± 1 nm. This is confirmed through far field scattering measurements on individual dimers which reveal a significant red shift in the plasmonic resonance peaks, consistent with the high dielectric environment due to the surrounding DNA. We use surface-enhanced Raman scattering (SERS) to demonstrate local field enhancements of several orders of magnitude through detection of a small number of dye molecules as well as short single-stranded DNA oligonucleotides."

According to the news editors, the research concluded: "This demonstrates that DNA origami is a powerful tool for the high-yield creation of SERS-active nanoparticle assemblies with reliable sub-5 nm gap sizes."

For more information on this research see: DNA origami based assembly of gold nanoparticle dimers for surface-enhanced Raman scattering. Nature Communications, 2014;5():3448. (Nature Publishing Group -; Nature Communications -

The news correspondents report that additional information may be obtained from V.V. Thacker, Cavendish Laboratory, JJ Thompson Avenue, Cambridge CB3 0HE, UK. Additional authors for this research include L.O. Herrmann, D.O. Sigle, T. Zhang, T. Liedl, J.J. Baumberg and U.F Keyser (see also DNA Research).

Keywords for this news article include: Europe, Cambridge, DNA Research, United Kingdom, Nanotechnology, Gold Nanoparticles, Emerging Technologies.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Science Letter

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