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New Findings Reported from National University Describe Advances in Capillary Electrophoresis

May 20, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- A new study on Capillary Electrophoresis is now available. According to news reporting originating in Santa Fe, Argentina, by NewsRx journalists, research stated, "This paper presents the development of a capillary electrophoresis method with diode array detector coupled to multivariate curve resolution-alternating least squares (MCR-ALS) to conduct the resolution and quantitation of a mixture of six quinolones in the presence of several unexpected components. Overlapping of time profiles between analytes and water matrix interferences were mathematically solved by data modeling with the well-known MCR-ALS algorithm."

The news reporters obtained a quote from the research from National University, "With the aim of overcoming the drawback originated by two compounds with similar spectra, a special strategy was implemented to model the complete electropherogram instead of dividing the data in the region as usually performed in previous works. The method was first applied to quantitate analytes in standard mixtures which were randomly prepared in ultrapure water. Then, tap water samples spiked with several interferences were analyzed."

According to the news reporters, the research concluded: "Recoveries between 76.7 and 125 % and limits of detection between 5 and 18 mu g L-1 were achieved."

For more information on this research see: Ultrafast quantitation of six quinolones in water samples by second-order capillary electrophoresis data modeling with multivariate curve resolution-alternating least squares. Analytical and Bioanalytical Chemistry, 2014;406(11):2571-2580. Analytical and Bioanalytical Chemistry can be contacted at: Springer Heidelberg, Tiergartenstrasse 17, D-69121 Heidelberg, Germany. (Springer - www.springer.com; Analytical and Bioanalytical Chemistry - www.springerlink.com/content/1618-2642/)

Our news correspondents report that additional information may be obtained by contacting M.R. Alcaraz, Univ Nacl Litoral, Catedra Quim Analit 1, Lab Desarrollo Analit & Quimiometria LADAQ, Fac Bioquim & Ciencias BiolCONICET, RA-3000 Santa Fe, Argentina. Additional authors for this research include L. Vera-Candioti, M.J. Culzoni and H.C. Goicoechea (see also Capillary Electrophoresis).

Keywords for this news article include: Santa Fe, Argentina, South America, Information Technology, Capillary Electrophoresis, Information and Data Modeling

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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