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Investigators at Tsinghua University Report Findings in DNA Research

May 20, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- A new study on DNA Research is now available. According to news originating from Beijing, People's Republic of China, by NewsRx correspondents, research stated, "A, multiplex DNA assay based on nanoparticle (NP) tags detection utilizing single particle mode inductively coupled plasma mass spectrometry (SP-ICP-MS) as ultra-sensitive readout has been demonstrated in the article. Three DNA targets associated with clinical diseases (HIV, HAV, and HBV) down to 1 pM were detected by DNA probes labeled with AuNPs, AgNPs, and PtNPs via DNA sandwich assay."

Our news journalists obtained a quote from the research from Tsinghua University, "Single nucleotide polymorphisms in genes can also be effectively discriminated. Since our method is unaffected by the sample matrix, it is well-suited for diagnostic applications."

According to the news editors, the research concluded: "Moreover, with the high sensitivity of SP-ICP-MS and the variety of NPs detectable by SP-ICP-MS, high-throughput DNA assay could be achieved without signal amplification or chain reaction amplification."

For more information on this research see: Multiplex DNA Assay Based on Nanoparticle Probes by Single Particle Inductively Coupled Plasma Mass Spectrometry. Analytical Chemistry, 2014;86(7):3541-3547. Analytical Chemistry can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Analytical Chemistry - www.pubs.acs.org/journal/ancham)

The news correspondents report that additional information may be obtained from S.X. Zhang, Tsinghua Univ, Dept. of Chem, Beijing Key Lab Microanalyt Methods & Instrumenta, Beijing 100084, People's Republic of China. Additional authors for this research include G.J. Han, Z. Xing, S.C. Zhang and X.R. Zhang (see also DNA Research).

Keywords for this news article include: Asia, Beijing, DNA Research, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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