- Company Presenting at 27th Annual International Society for
Antiviral Research (ISAR) on Specific Isomer -
The round was funded by a syndicate of angel groups led by the Life Science Angels (LSA) with other members of the syndicate including: BlueTree Allied Angels, The Angels’ Forum, Tech Coast Angels and Wilmington Investor Network, as well as several individual investors.
"Gemmus is very pleased to have the support of these experienced angel investors,” said
Data on Gemmus’ lead candidate, GP1681, will be presented in two posters at the 27th
The company’s candidate, GP1681, is an orally available eicosanoid being developed for the treatment of moderate to severe symptoms of influenza infection. Results of the trials demonstrate that influenza-infected mice which are treated with GP1681 are protected against death compared to placebo-treated mice. Uniquely, findings show that the increased survival is not the result of decreased viral titers but is due to a decrease in respiratory tract inflammation as demonstrated by a decrease in lung weight, lung score and pro-inflammatory cytokines in influenza-infected lungs.
“Gemmus management has a track record of success in drug development, especially in the area of anti-inflammatory products for high-value indications,” said
There are no prescription medications approved for the treatment of influenza subtypes other than neuraminidase inhibitors and amantadines, the latter which have recognized drug resistance issues. GP1681 represents a new and potentially groundbreaking approach to improved influenza therapies that focus on managing the immune system to reduce the symptoms of the infection. By reducing, but not eliminating, the level of pro-inflammatory cytokines in the lung, GP1681 and related compounds under development are “strain-agnostic” – they can treat infections even from influenza that has become drug resistant. This new approach to treating the flu allows for a faster return to normal activities than is possible with no treatment or with administration of antiviral therapies.
Gemmus is a privately held biotechnology company focused on the development of innovative pharmaceutical products for the treatment of infectious diseases by modulating the host response to the disease. Gemmus was founded in 2007 to develop EP2 and EP4 agonists for the treatment for the treatment of influenza and in-licensed technology from a major pharmaceutical company. The company has applied for and received an SBIR(NIH) and a QTDP competitive grant. Gemmus has its corporate office and labs in
Forward Looking Statements
Statements included in this press release that are not a description of historical facts may be forward looking statements.The inclusion of forward looking statements should not be regarded as a representation by Gemmus that any of its plans will be achieved.Actual results may differ materially from those anticipated or set forth in this press release due to the risks and uncertainties inherent in Gemmus' business including, without limitation, statements about difficulties or delays in developing, obtaining regulatory approval, manufacturing and commercializing its products, unexpected performance or side effects of its products, the scope and validity of its products’ patent protection, competition from other companies and its ability to obtain additional financing to support its operations.All forward looking statements are qualified in their entirety by this statement and Gemmus undertakes no obligation to revise or update this press release to reflect events or circumstances occurring after the date hereof.
For Gemmus Pharma