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New Findings Reported from Hankyong National University Describe Advances in Animal Genetics

May 6, 2014



By a News Reporter-Staff News Editor at China Weekly News -- A new study on Life Science Research is now available. According to news reporting originating from Anseong, South Korea, by VerticalNews correspondents, research stated, "The Korean Hanwoo cattle have been intensively selected for production traits, especially high intramuscular fat content. It is believed that ancient crossings between different breeds contributed to forming the Hanwoo, but little is known about the genomic differences and similarities between other cattle breeds and the Hanwoo."

Our news editors obtained a quote from the research from Hankyong National University, "In this work, cattle breeds were grouped by origin into four types and used for comparisons: the Europeans (represented by six breeds), zebu (Nelore), African taurine (N'Dama) and Hanwoo. All animals had genotypes for around 680000 SNPs after quality control of genotypes. Average heterozygosity was lower in Nelore and N'Dama (0.22 and 0.21 respectively) than in Europeans (0.26-0.31, with Shorthorn as outlier at 0.24) and Hanwoo (0.29). Pairwise F-ST analyses demonstrated that Hanwoo are more related to European cattle than to Nelore, with N'Dama in an intermediate position. This finding was corroborated by principal components and unsupervised hierarchical clustering. Using genome-wide smoothed F-ST, 55 genomic regions potentially under positive selection in Hanwoo were identified. Among these, 29 were regions also detected in previous studies. Twenty-four regions were exclusive to Hanwoo, and a number of other regions were shared with one or two of the other groups. These regions overlap a number of genes that are related to immune, reproduction and fatty acid metabolism pathways."

According to the news editors, the research concluded: "Further analyses are needed to better characterize the ancestry of the Hanwoo cattle and to define the genes responsible to the identified selection peaks."

For more information on this research see: Genome-wide detection of signatures of selection in Korean Hanwoo cattle. Animal Genetics, 2014;45(2):180-190. Animal Genetics can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; Animal Genetics - onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2052)

The news editors report that additional information may be obtained by contacting L.R. Porto-Neto, Hankyong Natl Univ, Dept. of Biotechnol, Anseong 456749, South Korea. Additional authors for this research include S.H. Lee, T.S. Sonstegard, C.P. Van Tassell, H.K. Lee, J.P. Gibson and C. Gondro.

Keywords for this news article include: Anseong, South Korea, Life Science Research

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Source: China Weekly News


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