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New Essential Amino Acids Findings from Shaanxi Normal University Described

February 14, 2014



By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Essential Amino Acids. According to news originating from Xi'an, People's Republic of China, by NewsRx correspondents, research stated, "A simple protocol to distinguish enantiomers is extremely intriguing and useful. In this study, we propose a low-cost, facile, sensitive method for visual chiral recognition of enantimers."

Our news journalists obtained a quote from the research from Shaanxi Normal University, "It is based on the inherent chirality of gold nanoparticles (AuNPs), and the unmodified AuNPs are used as chiral selector for D -and L-Tryptophan (Trp). In the presence of D-Trp, an appreciable red-to-blue color change of AuNPs solution can be observed, whereas no color change is found in the presence of L-Trp. The method can be used to detect D-Trp in the range of 0.2-10 mu M, and the limit of detection is 0.1 mu M. The chiral assay described in this work is easily readout with the naked eye or using a UV-vis spectrometer. Furthermore, the AuNPs can selectively adsorb D-Trp, and simple centrifugation can allow the precipitation of D-Trp with AuNPs and leave a net excess of the other enantiomer in solution, thus resulting in enantioseparation. In this method, AuNPs do not need any labeling or modifying with chiral molecules."

According to the news editors, the research concluded: "The method is more attractive because of its high sensitivity, low cost, ready availability and simple manipulation."

For more information on this research see: Visual chiral recognition of tryptophan enantiomers using unmodified gold nanoparticles as colorimetric probes. Analytica Chimica Acta, 2014;809():123-127. Analytica Chimica Acta can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Analytica Chimica Acta - www.elsevier.com/wps/product/cws_home/502681)

The news correspondents report that additional information may be obtained from L. Zhang, Shaanxi Normal Univ, Sch Chem & Chem Engn, Key Lab Analyt Chem Life Sci Shaanxi Prov, Xian 710062, People's Republic of China. Additional authors for this research include C.L. Xu, C.W. Liu and B.X. Li (see also Essential Amino Acids).

Keywords for this news article include: Asia, Xi'an, Tryptophan, Nanotechnology, Gold Nanoparticles, Aromatic Amino Acids, Emerging Technologies, Essential Amino Acids, People's Republic of China

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Source: Science Letter


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