News Column

Studies from Korea University Describe New Findings in Drug Delivery Systems

February 12, 2014

By a News Reporter-Staff News Editor at Biotech Week -- A new study on Drugs and Therapies is now available. According to news reporting originating from Seoul, South Korea, by NewsRx correspondents, research stated, "In cancer therapy, drug delivery is a complex process that aims to transit the cargo to the destination with as little damage to the normal tissue as possible. In the last decade, tremendous development and research on nanomedicine have been exploring an ideal system with efficient drug transportation and release property."

Our news editors obtained a quote from the research from Korea University, "For this end, series of barriers need to be circumvented by nanomedicine, including systemic barriers, such as biosurface adsorption, phagocytic clearance, bloodstream washing, interstitial pressure, degradation, as well as intracellular barriers, such as cell membrane reorganization and internalization, endo/lysosomal escape, cytosolic or subcellular localization. Rather than being random, these barriers follow a specific spatial-temporal sequence. Therefore, the nanocarriers have to be endowed with characteristics that are adaptive to particular biological milieu on systemic and intracellular levels."

According to the news editors, the research concluded: "To this end, we reviewed the correlations between the spatial-temporal sequences of drug delivery and nanocarrier characteristics in cancer therapy, as well as strategies to achieve efficient drug delivery upon both systemic and intracellular levels."

For more information on this research see: Spatial-temporal event adaptive characteristics of nanocarrier drug delivery in cancer therapy. Journal of Controlled Release, 2013;172(1):281-291. Journal of Controlled Release can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier -; Journal of Controlled Release -

The news editors report that additional information may be obtained by contacting M. Kong, Korea University, Grad Sch Biotechnol, Seoul 136701, South Korea. Additional authors for this research include H. Park, X.J. Cheng and X.G. Chen (see also Drugs and Therapies).

Keywords for this news article include: Asia, Seoul, Cancer, Oncology, South Korea, Nanomedicine, Nanotechnology, Drugs and Therapies, Drug Delivery Systems, Emerging Technologies

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Source: Biotech Week

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