News Column

Studies from Federal University Describe New Findings in Stem Cells

February 12, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Stem Cell Research have been published. According to news reporting from Recife, Brazil, by NewsRx journalists, research stated, "It is of current interest the identification of appropriate matrices for growing mesenchymal stem cells (MSC). These cells are able not only to regenerate themselves but also to differentiate into other type of functional cells, and so they have been extensively used in tissue engineering."

The news correspondents obtained a quote from the research from Federal University, "In this work, we have evaluated the use of electric impedance spectroscopy (EIS) to follow the adhesion of MSC from Wharton's jelly of the human umbilical cord (hWJMSC) on sugarcane biopolymers (SCB). Impedance spectra of the systems were obtained in the frequency range of 10(2)-10(5) Hz. An EIS investigation showed that when deposited on a metallic electrode SCB films prevent the passage of electrons between the solution and the metallic interface. The impedance spectra of hWJMSCs adhered on SCB revealed that there is a significant increase in the magnitude of the impedance when compared to that of pure SCB. The corresponding resistance (real part of the impedance) was even higher for the SCB-hWJMSC system than for SCB without cells on their surface, in an indication of an increased blockage to the electron transfers. The resistance charge transfer is extracted by curve-fitting the impedance spectra to an equivalent circuit model. Also, a shift of the phase angle to higher frequencies was obtained for SCB-hWJMSC system as a result from hWJMSC adhesion. Our study demonstrates that EIS is an appropriate method to evaluate the adhesion of MSC."

According to the news reporters, the research concluded: "SCB can be considered as a promising biomaterial for tissue engineering."

For more information on this research see: Dielectric study of the adhesion of mesenchymal stem cells from human umbilical cord on a sugarcane biopolymer. Journal of Materials Science-Materials in Medicine, 2014;25(1):229-237. Journal of Materials Science-Materials in Medicine can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands (see also Stem Cell Research).

Our news journalists report that additional information may be obtained by contacting A.S. Fragoso, Federal University of Pernambuco, Dept. of Bioquim, BR-50670901 Recife, PE, Brazil. Additional authors for this research include M.B. Silva, C.P. de Melo, J.L.A. Aguiar, C.G. Rodrigues, P.L. de Medeiros, J.F. Branco, C.A.S. Andrade and M.D.L. Oliveira.

Keywords for this news article include: Tissue Engineering, Biomedical Engineering, Biomedicine, Recife, Brazil, South America, Bioengineering, Stem Cell Research, Mesenchymal Stem Cells

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Source: Biotech Week

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