By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Bacterial Infections have been published. According to news reporting from Jerusalem, Israel, by NewsRx journalists, research stated, "Temporary restorative materials (TRMs) often rapidly lose their dimensional stability and antibacterial properties after exposure to humidity and bacterial infection. Quaternary ammonium polyethyleneimine (QPEI) nanoparticles (NP) are long-lasting, stable, biocompatible, and nonvolatile antibacterial polymers."
The news correspondents obtained a quote from the research from Hebrew University, "In the present study, we incorporated QPEI NP into standard TRMs and examined their influence on dimensional stability and their ability to reduce bacterial leakage. A modified split-chamber model was used in vitro to test calcium sulfate-based and zinc oxide-eugenol-based TRMs (Coltosol and IRM, respectively). Both materials were tested with and without 2% wt/wt incorporated QPEI NP for fluid and bacterial leakage. The calcium sulfate-based TRM displayed the lowest microleakage and highest antibacterial resistance. Two-way A NOVA analysis of the fluid transport test results showed that incorporation of 2% wt/wt QPEI NP significantly increased the sealing ability of both TRMs (p <.01). Analysis of survival curves by the Kaplan-Meier method showed that the calcium sulfate-based TRM with 2% wt/wt QPEI NP survived the bacterial load significantly more effectively than did the zinc oxide-eugenol-based TRM (p <.0001). Incorporation of 2% w/w QPEI NP may prominently improve the sealability and the antibacterial properties of TRMs."
According to the news reporters, the research concluded: "TRMs incorporating antibacterial nanoparticles may be clinically advantageous for sealing the endodontic access cavity to avoid reinfection of the root canal system during endodontic treatment."
For more information on this research see: Antibacterial temporary restorative materials incorporating polyethyleneimine nanoparticles. Quintessence International, 2013;44(3):209-16 (see also Bacterial Infections).
Our news journalists report that additional information may be obtained by contacting I. Abramovitz, Dept. of Endodontics, Hebrew University-Hadassah School of Dental Medicine, Jerusalem, Israel. Additional authors for this research include N. Beyth, Y. Paz, E.I. Weiss and S. Matalon.
Keywords for this news article include: Asia, Israel, Alkenes, Minerals, Polyenes, Jerusalem, Chemistry, Zinc Oxide, Hydrocarbons, Sulfur Acids, Calcium Sulfate, Sulfur Compounds, Calcium Compounds, Polyethyleneimine, Inorganic Chemicals, Bacterial Infections and Mycoses.
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