News Column

Researchers at Uppsala University Target Neuropsychopharmacology

February 12, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Fresh data on Neuropsychopharmacology are presented in a new report. According to news reporting from Uppsala, Sweden, by NewsRx journalists, research stated, "Mass spectrometry imaging is a powerful tool for directly determining the distribution of proteins, peptides, lipids, neurotransmitters, metabolites and drugs in neural tissue sections in situ. Molecule-specific imaging can be achieved using various ionization techniques that are suited to different applications but which all yield data with high mass accuracies and spatial resolutions."

The news correspondents obtained a quote from the research from Uppsala University, "The ability to simultaneously obtain images showing the distributions of chemical species ranging from metal ions to macromolecules makes it possible to explore the chemical organization of a sample and to correlate the results obtained with specific anatomical features. The imaging of biomolecules has provided new insights into multiple neurological diseases, including Parkinson's and Alzheimer's disease. Mass spectrometry imaging can also be used in conjunction with other imaging techniques in order to identify correlations between changes in the distribution of important chemical species and other changes in the properties of the tissue. Here we review the applications of mass spectrometry imaging in neuroscience research and discuss its potential."

According to the news reporters, the research concluded: "The results presented demonstrate that mass spectrometry imaging is a useful experimental method with diverse applications in neuroscience."

For more information on this research see: Mass spectrometry imaging, an emerging technology in neuropsychopharmacology. Neuropsychopharmacology, 2014;39(1):34-49. Neuropsychopharmacology can be contacted at: Nature Publishing Group, 345 Park Avenue South, New York, NY 10010-1707, USA. (Nature Publishing Group -; Neuropsychopharmacology -

Our news journalists report that additional information may be obtained by contacting M. Shariatgorji, Dept. of Pharmaceutical Biosciences, Biomolecular Imaging and Proteomics, National Laboratory for Mass Spectrometry Imaging, Uppsala University, Uppsala, Sweden. Additional authors for this research include P. Svenningsson and P.E Andren (see also Neuropsychopharmacology).

Publisher contact information for the journal Neuropsychopharmacology is: Nature Publishing Group, 345 Park Avenue South, New York, NY 10010-1707, USA.

Keywords for this news article include: Sweden, Uppsala, Therapy, Technology, Neuropsychopharmacology.

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Source: Biotech Week

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