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Reports on Stem Cells from University of London Imperial College Provide New Insights

February 10, 2014

By a News Reporter-Staff News Editor at Stem Cell Week -- A new study on Stem Cell Research is now available. According to news originating from London, United Kingdom, by NewsRx correspondents, research stated, "In recent years, technical developments in mouse genetics and imaging equipment have substantially advanced our understanding of hematopoietic stem cells (HSCs) and their niche."

Our news journalists obtained a quote from the research from the University of London Imperial College, "The availability of numerous Cre strains for targeting HSCs and microenvironmental cells provides extensive flexibility in experimental design, but it can also pose significant challenges due to strain-specific differences in cell specificity. Here we outline various genetic approaches for isolating, detecting, and ablating HSCs and niche components and provide a guide for advantages and caveats to consider."

According to the news editors, the research concluded: "We also discuss opportunities and limitations presented by imaging technologies that allow investigation of HSC behavior in situ."

For more information on this research see: Deciphering Hematopoietic Stem Cells in Their Niches: A Critical Appraisal of Genetic Models, Lineage Tracing, and Imaging Strategies. Cell Stem Cell, 2013;13(5):520-533. Cell Stem Cell can be contacted at: Cell Press, 600 Technology Square, 5TH Floor, Cambridge, MA 02139, USA. (Elsevier -; Cell Stem Cell -

The news correspondents report that additional information may be obtained from C. Joseph, University of London Imperial College, Dept. of Life Sci, London SW7 2AZ, United Kingdom. Additional authors for this research include J.M. Quach, C.R. Walkley, S.W. Lane, C. Lo Celso and L.E. Purton (see also Stem Cell Research).

Keywords for this news article include: London, Europe, Genetics, Hematology, United Kingdom, Bone Marrow Cells, Stem Cell Research, Hematopoietic Stem Cells

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Source: Stem Cell Week

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