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Reports from Indian Institute of Technology Add New Data to Findings in Serine Endopeptidases

February 11, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Enzymes and Coenzymes. According to news originating from New Delhi, India, by NewsRx correspondents, research stated, "The synergy of ultrasonication and the exposure to light radiation was found to be necessary in the formation of nanocomposites of silver and a protease alpha chymotrypsin. The reaction was carried out in aqueous medium and the process took just less than 35 min."

Our news journalists obtained a quote from the research from the Indian Institute of Technology, "Ultrasonication alone formed very negligible number of nanoparticles of 100 nm. The effects of pH (in the range of 3-5, 9-10), ultrasonication time periods (0-30 min), ultrasonication intensity (33-83 W cm(-2)), energy of light radiation (short UV, long UV and Fluorescent light) and time period of exposure (5-60 min) to different light radiations were studied. The formation of nanocomposites under these effects was followed by surface plasmon resonance (SPR) spectra, dynamic light scattering (DLS), transmission electron microscopy (TEM). Ag-chymotrypsin nanocomposites of sizes ranging from 13 to 72 nm were formed using the synergy of ultrasonication and exposure to short UV radiation."

According to the news editors, the research concluded: "Results show that ultrasonication promoted nuclei formation, growth and reduction of polydispersity by Ostwald ripening."

For more information on this research see: Green synthesis of nanocomposites consisting of silver and protease alpha chymotrypsin. Ultrasonics Sonochemistry, 2013;20(4):1054-61. (Elsevier -; Ultrasonics Sonochemistry -

The news correspondents report that additional information may be obtained from J. Mukherjee, Dept. of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India. Additional authors for this research include D. Malhotra, S. Gautam and M.N Gupta (see also Enzymes and Coenzymes).

Keywords for this news article include: Asia, India, Protease, New Delhi, Chymotrypsin, Nanocomposite, Nanotechnology, Peptide Hydrolases, Emerging Technologies, Enzymes and Coenzymes, Serine Endopeptidases.

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Source: Life Science Weekly

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