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Findings from National Taiwan University in the Area of DNA Research Described

February 11, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on DNA Research are discussed in a new report. According to news reporting originating from Taipei, Taiwan, by NewsRx correspondents, research stated, "A novel colorimetric approach to sense DNA samples was demonstrated successfully based on a concept of hybridization-mediated growth of gold nanoparticles probes (AuNP probes). The growth size and conformation of the probes are dominated by DNA samples that hybridize with the probes."

Our news editors obtained a quote from the research from National Taiwan University, "The growth probes serve as nanoparticle biosensors that can be utilized to analyze concentrations of DNA samples or to discriminate mismatches of DNA samples to the probes (complementarity of DNA) in terms of size- and shape-dependence optical properties. By means of the proposed method, not only the semi-quantitation of target DNA but also the differentiation of DNA mismatches can be readily achieved with a naked eye or simple spectrophotometer."

According to the news editors, the research concluded: "This method features small consumption of reagents, a satisfactory detection limit (about 60 nM), a small duration of assay (a couple of minutes), and a simple procedure without thermal control."

For more information on this research see: Colorimetric determination of DNA concentration and mismatches using hybridization-mediated growth of gold nanoparticle probes. Sensors and Actuators B-Chemical, 2014;192():77-82. Sensors and Actuators B-Chemical can be contacted at: Elsevier Science Sa, PO Box 564, 1001 Lausanne, Switzerland (see also DNA Research).

The news editors report that additional information may be obtained by contacting W.F. Fang, National Taiwan University, Dept. of Internal Med Emergency Med, Taipei 100, Taiwan. Additional authors for this research include W.J. Chen and J.T. Yang.

Keywords for this news article include: Asia, Taipei, Taiwan, DNA Research, Nanotechnology, Gold Nanoparticles, Emerging Technologies

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Source: Life Science Weekly

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