Iranian researchers used nanoparticles for producing drug carriers that have high adsorption ability inside liver and spleen but have low adsorption in other body organs.
Among important characteristics of the research, mention can be made of determining the adsorption dosage of nanoparticles in case they are attached to gallium 67 radioisotope,
The researchers initially purified the final product by selecting the appropriate method for marking nanoparticles with gallium 67. Then, they controlled the quality and investigated the stability of the product.
Animal studies and determination of the adsorption dosage in humans by using animal data were among other activities carried out by the researchers.
According to Dr.
"Among the results of the research, mention can be made of the possibility of using such nanoparticles for drug delivery to liver and the application of nanoparticles by using alpha-emitting radioisotope," he said.
"Another important point is that the nanoparticles are not adsorbed in other body organs because they are used for drug delivery to the liver. Taking into consideration the data obtained from the research, it can be concluded that these nanoparticles are not desirable for the targeted drug delivery to other organs, except liver."
The research has been carried out by Dr.
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