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Study Results from University of Shizuoka Update Understanding of Nanoparticles

March 4, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Nanoparticles are discussed in a new report. According to news reporting originating in Shizuoka, Japan, by NewsRx journalists, research stated, "Gene silencing mediated by RNA interference (RNAi) is expected to have a beneficial impact on the treatment of many diseases because of its potency, selectivity and versatility."

The news reporters obtained a quote from the research from the University of Shizuoka, "To maximize the potential of RNAi effectors such as small interfering RNA and microRNA in clinical therapy, the development of a practical delivery system is required, especially for systemic administration. Recent studies demonstrated that chemical modification of these small RNAs and/or encapsulation of them into lipid nanoparticles is a promising strategy to achieve targeted delivery via systemic administration."

According to the news reporters, the research concluded: "In this review article, we introduce recent progress of the research on systemic delivery systems for RNAi therapeutics and consider crucial elements for the design of lipid nanoparticles as a small RNA vector."

For more information on this research see: Systemic Delivery of Small RNA Using Lipid Nanoparticles. Biological & Pharmaceutical Bulletin, 2014;37(2):201-205. Biological & Pharmaceutical Bulletin can be contacted at: Pharmaceutical Soc Japan, 2-12-15Shibuya, Shibuya-Ku, Tokyo, 150-0002, Japan (see also Nanoparticles).

Our news correspondents report that additional information may be obtained by contacting T. Asai, University of Shizuoka, Sch Pharmaceut Sci, Dept. of Med Biochem, Suruga Ku, Shizuoka 4228526, Japan.

Keywords for this news article include: Asia, Japan, Shizuoka, Nanotechnology, Emerging Technologies

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Source: Life Science Weekly


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