The patent's assignee for patent number 8652293 is
News editors obtained the following quote from the background information supplied by the inventors: "Biological and synthetic tissue adhesives have been developed as alternatives to sutures and staples for adhering biological tissue. Examples of biological tissue adhesives include fibrin glues. Examples of synthetic tissue adhesives include cyanoacrylates, urethane prepolymers, and gelatin-resorcinol-formaldehyde. Applications of adhesives to biological tissue range from soft (connective) tissue adhesion to hard (calcified) tissue adhesion. Soft tissue adhesive are used both externally and internally for wound closure and sealing. Hard tissue adhesive adhesives are used in applications that include bonding prosthetic materials to teeth and bone."
As a supplement to the background information on this patent, VerticalNews correspondents also obtained the inventors' summary information for this patent: "An adhesive is described that includes the reaction product of: (a) an isocyanate component having an average functionality of at least 2; (b) an active hydrogen component having an average functionality greater than 2.1; and © an ionic salt component having an average hydroxyl or amino functionality, or combination thereof, of at least 1. The adhesive is moisture-curable and biodegradable, and may be applied to soft or hard biological tissue.
"The term 'component' refers to single compounds, and to blends of different compounds.
"The adhesive may also include a catalyst, solvent, volatile diluent, non-volatile diluent, or combination thereof. The term 'volatile' diluent refers to a diluent having a boiling point, at atmospheric pressure, of less than or equal to 40.degree. C. Conversely, a 'nonvolatile' diluent refers to a diluent having a boiling point, at atmospheric pressure, of greater than 40.degree.
"Inclusion of the ionic salt, which reacts with the isocyanate component of the composition and thus becomes covalently incorporated into the adhesive, increases the hydrophilicity of the adhesive relative to an adhesive that lacks the ionic salt. The increased hydrophilicity, in turn, may improve bond strength between the adhesive and biological tissue. It may also improve the solubility of other hydrophilic agents, such as hydroxyl group-containing compounds, which would further increase the overall hydrophilicity of the adhesive.
"The details of one or more embodiments are set forth in the description below. Other features, objects, and advantages will be apparent from the description, drawing, and the claims."
For additional information on this patent, see:
Keywords for this news article include: Tissue Engineering, Biomedical Engineering, Biomedicine, Bioengineering, Fibrin Sealant, Medical Devices.
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
Most Popular Stories
- Dmytro Firtash, Ukrainian Billionaire, Arrested in Vienna
- Obama, Ukraine Discuss Russian Incursion in Crimea
- Calumet Photo Files for Bankruptcy
- Ukraine Loan Delayed While Congress Goes on Vacation
- Ukraine Moves Closer to Joining E.U.
- Venezuela Death Toll Reaches 28
- Federal Gov't Deficit Continues to Decline
- Russia Holds Large Military Drills in South
- Navarro Celebrates 2 Years of Vida Mia
- Herbalife Puts Off Meeting for Icahn Talks