News Column

New DNA Research Findings from Ohio State University Described

March 4, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on DNA Research. According to news reporting out of Columbus, Ohio, by NewsRx editors, research stated, "DNA origami enables fabrication of precise nanostructures by programming the self-assembly of DNA. While this approach has been used to make a variety of complex 2D and 3D objects, the mechanical functionality of these structures is limited due to their rigid nature."

Our news journalists obtained a quote from the research from Ohio State University, "We explore the fabrication of deformable, or compliant, objects to establish a framework for mechanically functional nanostructures. This compliant design approach is used in macroscopic engineering to make devices including sensors, actuators, and robots. We build compliant nanostructures by utilizing the entropic elasticity of single-stranded DNA (ssDNA) to locally bend bundles of double-stranded DNA into bent geometries whose curvature and mechanical properties can be tuned by controlling the length of ssDNA strands. We demonstrate an ability to achieve a wide range of geometries by adjusting a few strands in the nanostructure design. We further developed a mechanical model to predict both geometry and mechanical properties of our compliant nanostructures that agrees well with experiments."

According to the news editors, the research concluded: "Our results provide a basis for the design of mechanically functional DNA origami devices and materials."

For more information on this research see: DNA Origami Compliant Nanostructures with Tunable Mechanical Properties. ACS Nano, 2014;8(1):27-34. ACS Nano can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; ACS Nano - www.pubs.acs.org/journal/ancac3)

Our news journalists report that additional information may be obtained by contacting L.F. Zhou, Ohio State University, Dept. of Mech & Aerosp Engn, Columbus, OH 43210, United States. Additional authors for this research include A.E. Marras, H.J. Su and C.E. Castro (see also DNA Research).

Keywords for this news article include: Ohio, Columbus, DNA Research, United States, Nanostructural, Nanostructures, Nanotechnology, Emerging Technologies, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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