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Findings from Kagawa University in Glycoside Hydrolases Reported

March 4, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Enzymes and Coenzymes. According to news reporting from Kagawa, Japan, by NewsRx journalists, research stated, "Rosmarinic acid extract with potent biological activities was successfully isolated by supramolecular technique and solvent extraction from Perilla leaves. By the supramolecular complex which was formed from flavocommelin and Perilla leaf extract as initial materials, the supernatant containing rosmarinic acid was isolated."

The news correspondents obtained a quote from the research from Kagawa University, "Rosmarinic acid extract (62.9 +/- 4.5% purity) was partly purified by partitioning ethyl acetate and water. Rosmarinic acid extract exhibited high total phenolic content of 433.9 +/- 58.6 mu g/mg of gallic acid equivalent, effective DPPH radical scavenging activity (SC50 of 5.5 +/- 0.2 mu g/mL), antiallergic activity (IC50 of 52.9 +/- 6.7 mu g/mL), and a-glucosidase inhibitory activity (IC50 of 0.23 +/- 0.01 mg/mL)."

According to the news reporters, the research concluded: "Rosmarinic acid extract shows high potential for diabetes mellitus and allergy treatments by inhibiting a-glucosidase activity and measuring beta-hexosaminidase, related to life-style disease."

For more information on this research see: Rosmarinic Acid Extract for Antioxidant, Antiallergic, and alpha-Glucosidase Inhibitory Activities, Isolated by Supramolecular Technique and Solvent Extraction from Perilla Leaves. Journal of Agricultural and Food Chemistry, 2014;62(4):885-892. Journal of Agricultural and Food Chemistry can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society -; Journal of Agricultural and Food Chemistry -

Our news journalists report that additional information may be obtained by contacting F.X. Zhu, Kagawa Univ, Dept. of Appl Biol Sci, Miki, Kagawa 7610795, Japan. Additional authors for this research include T. Asada, A. Sato, Y. Koi, H. Nishiwaki and H. Tamura (see also Enzymes and Coenzymes).

Keywords for this news article include: Asia, Antioxidants, Japan, Kagawa, Nanotechnology, Supramolecular, Protective Agents, alpha-Glucosidases, Glycoside Hydrolases, Emerging Technologies, Enzymes and Coenzymes

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Source: Life Science Weekly

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