The new technology separates perfect peptides from those that do not make the grade, says
These atoms bind to either the perfect peptides or the unfinished ones, but not to both. The polymerized peptides become insoluble and precipitate out of the solution. "Just take the solution out, and the peptides are separated," said Fang.
The method works in about two hours, much faster than a similar process Fang developed a few years ago. And it works equally well for DNA sequences.
The process has other advantages. It is cheaper and requires less labor than existing peptide purification methods, it can handle large batches of peptides at a time, and it generates less waste. "Other methods use a large amount of organic solvents, with a waste-to-product ratio of about 1,000:1. Our waste-to-product ratio is 50:1, maximum," said Fang. "And it takes less time."
Fang has been issued a patent for his discovery and is exploring its commercial potential. "I'm excited about the progress we've made," he said. "Peptide drugs are used to fight cancer, inflammation, diseases of the central nervous system, viral diseases like HIV... This gives us a chance to make a difference in people's lives."
Keywords for this news article include: HIV/AIDS, Peptides, Proteins, Amino Acids,
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
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