Ignyta, Inc., an oncology precision medicine biotechnology company, announced that Sara Zaknoen, M.D., has been appointed as Chief Medical Officer, assuming full-time responsibilities for the role from James L. Freddo, M.D., who was previously serving as Ignyta's Chief Medical Officer on a consulting basis.
"Sara brings to Ignyta a wealth of experience in the life sciences field, particularly in pharmaceutical drug development and clinical oncology research, and the ability to combine a people focused approach with deep scientific acumen," said Jonathan Lim, M.D., Chairman and CEO of Ignyta. "Her extensive experience in both biotech and large pharma and prior accomplishments in oncology drug development will make her instrumental to the company's success as we strive to create value for patients with our proprietary oncology drug candidates. We also want to thank Jim for his outstanding contributions to Ignyta as our consulting CMO, and look forward to continuing to work with him as he serves Ignyta in an advisory capacity."
In a release, the Company said that Dr. Zaknoen was previously Chief Medical Officer of Polynoma from May 2012 to January 2014, where she led the medical efforts of the adaptive Phase 3 pivotal Melanoma Antigen Vaccine Immunotherapy Study (MAVIS). From January 2007 until February 2012, Dr. Zaknoen served as Chief Medical Officer of Tragara Pharmaceuticals, Inc., where she spearheaded the design and successful completion of Phase 1 and 2 studies for two compounds. From September 2006 to December 2006, Dr. Zaknoen served as Chief Medical Officer of Cabrellis Pharmaceuticals Corp., contributing to the sale of Cabrellis to Pharmion Corp. in November 2006.
Dr. Zaknoen served as Executive Director of Phase 2/3 Clinical Oncology Research of Novartis Pharmaceuticals Corp. from September 2002 until September 2006. At Novartis, Dr. Zaknoen directed global development of five drugs in Phase 2 and 3, including expanding the label for Gleevec and driving the registration for Tasigna, and she served as clinical representative to the Business Development & Licensing team for the Oncology Business Unit. From April 1998 to September 2002, Dr. Zaknoen was Director of Clinical Oncology Research at Schering-Plough Research Institute, where she was a key member of the team directing the registration and launch of Temodar.
Dr. Zaknoen's prior positions include Assistant Professor of Medicine at the University of Cincinnati Medical Center; Director of Experimental Therapeutics at the Western Pennsylvania Hospital, Western Pennsylvania Cancer Institute; Medical Staff Fellow at the National Cancer Institute; and internship, residency and fellowship in hematology/oncology at the University of Minnesota.
Ignyta, Inc. is a biotechnology company developing precision medicine with integrated Rx/Dx solutions for cancer patients.
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