A University of Adelaide PhD student has developed a computer model for simulating cancer tumour growth and treatment which is attracting interest from around the world as a first-line assessment of potential treatments.
The first of its kind in the world, the model simulates the growth of tumour from single cells and the effect of cancer treatments such as radiation at the nanoscale level.
"Unlike other cancer models, this model simulates the tumour growth and effects of various treatments, right through to the probability of survival of cells and whether they have been destroyed by the treatment," says
The research, supervised by Associate Professor
"We model individual radiation particle interactions on scales smaller than the size of a water molecule," says
The model is now being used to study new cancer treatment techniques such as the use of gold-nanoparticles to reduce the radiation dose needed to destroy tumours, and so reduce or eliminate acute radiation side-effects.
"Targeting and destroying an individual cancer cell in the human body is a bit like spotting a fly from several kilometres away," says
"The beauty of this model is that we can investigate the actions of new treatments such as gold nano-particle therapy to see what happens when we can't look at it experimentally. The processes are happening on such a small scale that computer modelling is the only way of understanding how they are working.
"We can use the model to investigate what will happen with any therapy so we can verify it as a potential treatment and then, if it's looking promising, go ahead with clinical trials."
Over the next year, the model will be further developed in many international collaborations including
The model's algorithms also will be released to researchers around the world this year.
TNS 30FurigayJof 140220-4643236 30FurigayJof
Most Popular Stories
- Chobani Counters Competition With Expanded Lineup
- Pope Francis, Huge Crowd Joyously Celebrate Easter
- Automakers Turn to China to Fuel Sales Growth
- GM Boosting China Production Capacity
- GOP Making Bold Play for Oregon Senate Seat
- Delay in Ferry Evacuation Puzzles Maritime Experts
- Confusion, Anger as Sunken Ferry's Relatives Wait
- Report: Iran VP Says Row Over Reactor Resolved
- NASA's Space Station Robonaut Finally Getting Legs
- Putin: No Blocks to Boosting Relations With West