By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Amino Acids. According to news originating from Higashi Hiroshima, Japan, by NewsRx correspondents, research stated, "We elucidated theoretically and experimentally that counter-ions in background electrolyte (BGE) play a role of booster for electrokinetic injection (EKI) for the determination of cationgenic weak electrolytes and amino acids in neutral aqueous solutions using capillary electrophoresis (CE). The pH change in the sample solution caused by the migration of counter-ions resulted in the increase of analyte mobility and hence the increase of the amount of analyte injected into the capillary."
Our news journalists obtained a quote from the research from Hiroshima University, "This type of EKI was named as counter-ion boosted EKI. Using the counter-ion boosted EKI-capillary zone electrophoresis (CZE), the limit of detections (LODs,S/N=3) for creatinine (4.8 nM) and L-histidine (9.0 nM) were lowest ever achieved by CE with UV detection. The RSDs (n=3) of the migration time for creatinine and L-histidine were obtained as 0.35% and 0.34%, for peak areas of 13% and 12%, and for peak heights of 12% and 8.5%, respectively."
According to the news editors, the research concluded: "The concentrations of creatinine and L-histidine in a urine sample obtained by the proposed method were within those reported with a good recovery."
For more information on this research see: Role of counter-ions in background electrolyte for the analysis of cationgenic weak electrolytes and amino acids in neutral aqueous solutions by capillary electrophoresis with electrokinetic injection. Journal of Chromatography A, 2014;1326():130-133. Journal of Chromatography A can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Journal of Chromatography A - www.elsevier.com/wps/product/cws_home/502688)
The news correspondents report that additional information may be obtained from T. Hattori, Hiroshima University, Grad Sch Engn, Higashihiroshima, Hiroshima 7398527, Japan. Additional authors for this research include K. Fukushi and T. Hirokawa (see also Amino Acids).
Keywords for this news article include: Asia, Japan, Peptides, Proteins, Amino Acids, Electrolytes, Nanotechnology, Electrokinetics, Higashi Hiroshima, Inorganic Chemicals, Emerging Technologies, Capillary Electrophoresis
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