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Investigators from University of Denver Release New Data on Applied Clay Science

February 28, 2014

By a News Reporter-Staff News Editor at Science Letter -- New research on Science is the subject of a report. According to news reporting out of Denver, Colorado, by NewsRx editors, research stated, "A novel flow-based technique to determine effective binding constants between caffeine and dispersed Laponite-RD particles in aqueous dispersions is presented. The technique, which is based on wide-bore hydrodynamic chromatography principles, exploits diffusion coefficient and flow profile differences between caffeine and Laponite-RD."

Our news journalists obtained a quote from the research from the University of Denver, "A high-pressure liquid chromatography pump is used to create a laminar flow of mobile phase through a 0.25 mm diameter capillary; flow conditions are optimized in the capillary to exploit differences in diffusion coefficients of the dispersed Laponite-RD particles and caffeine. Different flow profiles for Laponite-RD and caffeine result enabling a deconvolution algorithm to determine the concentrations of caffeine associated with the Laponite-RD, a model nanoparticle, as well as the caffeine free in solution."

According to the news editors, the research concluded: "Using these data, binding isotherms are presented from which an effective binding constant of caffeine associated with Laponite-RD can be obtained."

For more information on this research see: A hydrodynamic method for the measurement of Laponite-RD caffeine binding. Applied Clay Science, 2014;87():197-204. Applied Clay Science can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier -; Applied Clay Science -

Our news journalists report that additional information may be obtained by contacting K.J. Sorauf, Univ Denver, Dept. of Chem & Biochem, Denver, CO 80208, United States. Additional authors for this research include D.E. Connors, T.A. Wells and K.E. Miller (see also Science).

Keywords for this news article include: Denver, Science, Colorado, United States, North and Central America

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Source: Science Letter

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