News Column

Recent Studies from California Institute of Technology Add New Data to Biomedicine and Biomedical Engineering

February 26, 2014



By a News Reporter-Staff News Editor at Biotech Week -- Researchers detail new data in Biotechnology. According to news reporting originating in Pasadena, California, by NewsRx journalists, research stated, "Magnetic spectroscopy allows for characterization of the magnetic susceptibility of magnetic beads across a broad frequency range. This enables differentiation and quantification of multiple beads of varying types concurrently present in the active volume of a sensor's surface."

The news reporters obtained a quote from the research from the California Institute of Technology, "A magnetic spectrometer can be used for multi-probe tagging and identification akin to multicolor fluorescent bio-sensing. We propose a new sensing methodology to perform magnetic spectroscopy and analyze various important design parameters such as SNR and gain uniformity. We present a proof-of-concept design of a fully integrated CMOS magnetic spectrometer that can detect, quantify, and characterize magnetic materials in the 1.1 GHz to 3.3 GHz frequency range, where we demonstrate magnetic multiplexing capability using a mixture of two different kinds of magnetic beads. The sensor consumes less than 2 mW of DC power within the whole frequency range, requires no external biasing magnetic fields, is implemented in a standard CMOS process, and can be powered and operated completely from a USB interface."

According to the news reporters, the research concluded: "The magnetic spectrometer not only increases the throughput and multiplexing of biosensing experiments for a given sensor area, but also can enable additional applications, such as magnetic flow cytometry and signal-collocation assays of multiple probes."

For more information on this research see: Design and Implementation of an Integrated Magnetic Spectrometer for Multiplexed Biosensing. IEEE Transactions on Biomedical Circuits and Systems, 2013;7(6):773-784. IEEE Transactions on Biomedical Circuits and Systems can be contacted at: Ieee-Inst Electrical Electronics Engineers Inc, 445 Hoes Lane, Piscataway, NJ 08855-4141, USA. (Institute of Electrical and Electronics Engineers - www.ieee.org/; IEEE Transactions on Biomedical Circuits and Systems - ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=4156126)

Our news correspondents report that additional information may be obtained by contacting C. Sideris, California Institute of Technology, Dept. of Elect Engn, Pasadena, CA 91125, United States (see also Biotechnology).

Keywords for this news article include: Biotechnology, Pasadena, California, United States, North and Central America

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Source: Biotech Week


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