By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Gram-Positive Bacteria. According to news reporting originating from Giessen, Germany, by NewsRx correspondents, research stated, "Emerging technologies in functional genomics and proteomics provide a way of achieving high-throughput analyses, understanding effects on protein populations and sub-populations and follow up environmental stresses. To accomplish these, the action of homemade spherical Silver nanoparticles colloidal suspension (AgNPs) against Bacillus thuringiensis (isolate from Oryza sativa L rhizosphere) was investigated by a proteomic approach (2-DE and NanoLC/FT-ICR MS identification)."
Our news editors obtained a quote from the research from the University of Giessen, "Thirty four responsive (up/down regulated) proteins were identified. Proteomic results revealed that an exposure of B. thuringiensis cells with different concentrations of AgNPs resulted in an accumulation of envelope protein precursors, indicative of the dissipation of a proton motive force. Identified proteins are involved in oxidative stress tolerance, metal detoxification, transcription and elongation processes, protein degradation, cytoskeleton remodeling and cell division."
According to the news editors, the research concluded: "The expression pattern of these proteins and their possible involvement in the nontoxicity mechanisms were discussed."
For more information on this research see: Proteomics study of silver nanoparticles toxicity on Bacillus thuringiensis. Ecotoxicology and Environmental Safety, 2014;100():122-130. Ecotoxicology and Environmental Safety can be contacted at: Academic Press Inc Elsevier Science, 525 B St, Ste 1900, San Diego, CA 92101-4495, USA. (Elsevier - www.elsevier.com; Ecotoxicology and Environmental Safety - www.elsevier.com/wps/product/cws_home/622819)
The news editors report that additional information may be obtained by contacting F. Mirzajani, University of Giessen, Inst Inorgan & Analyt Chem, D-35392 Giessen, Germany. Additional authors for this research include H. Askari, S. Hamzelou, Y. Schober, A. Rompp, A. Ghassempour and B. Spengler (see also Gram-Positive Bacteria).
Keywords for this news article include: Europe, Giessen, Germany, Peptides, Proteins, Proteomics, Amino Acids, Bacillaceae, Nanoparticle, Nanotechnology, Gram-Positive Rods, Emerging Technologies, Bacillus thuringiensis, Gram-Positive Bacteria, Endospore-Forming Bacteria, Gram-Positive Endospore-Forming Rods
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