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Researchers from Instituto de Salud Carlos III Describe Findings in Nanoparticles

February 21, 2014

By a News Reporter-Staff News Editor at Science Letter -- Current study results on Nanoparticles have been published. According to news reporting out of Madrid, Spain, by NewsRx editors, research stated, "Different generations of PPV-PAMAM hybrid dendrimers have been prepared and characterized. Our initial studies showed the high tendency of these materials to aggregate and form nanoassemblies in different media."

Our news journalists obtained a quote from the research from Instituto de Salud Carlos III, "Nile Red experiments and DLS measurements allowed us to determine the critical aggregation concentration (CAC) and the size of the aggregates, which have also been used to stabilize small gold nanoparticles. The nanoparticles influence the assembly and optical properties of the dendrimer molecules and lead to strong quenching of their intrinsic fluorescence."

According to the news editors, the research concluded: "Nevertheless, these gold particles will be very useful as biomarkers in living cells by means of electron microscopy because of their high electron contrast."

For more information on this research see: PPV-PAMAM Hybrid Dendrimers: Self-Assembly and Stabilization of Gold Nanoparticles. Macromolecules, 2013;46(18):7316-7324. Macromolecules can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society -; Macromolecules -

Our news journalists report that additional information may be obtained by contacting J. Guerra, Inst Salud Carlos III, CIBERNED, Madrid 28071, Spain. Additional authors for this research include A.C. Rodrigo, S. Merino, J. Tejeda, J.C. Garcia-Martinez, P. Sanchez-Verdu, V. Cena and J. Rodriguez-Lopez (see also Nanoparticles).

Keywords for this news article include: Spain, Madrid, Europe, Nanotechnology, Gold Nanoparticles, Emerging Technologies

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Source: Science Letter

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