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New Findings from Center for Biomedical Engineering in the Area of Scientific Instruments Described

February 21, 2014



By a News Reporter-Staff News Editor at Science Letter -- Data detailed on Scientific Instruments have been presented. According to news reporting originating in New York City, New York, by NewsRx journalists, research stated, "This paper presents a combined ultrasound and photoacoustic (PA) imaging (PAI) system used to obtain high-quality, co-registered images of mouse-embryo anatomy and vasculature. High-frequency ultrasound (HFU, >20 MHz) is utilized to obtain high-resolution anatomical images of small animals while PAI provides high-contrast images of the vascular network."

The news reporters obtained a quote from the research from Center for Biomedical Engineering, "The imaging system is based on a 40 MHz, 5-element, 6 mm aperture annular-array transducer with a 800 ?m diameter hole through its central element. The transducer was integrated in a cage-plate assembly allowing for a collimated laser beam to pass through the hole so that the optical and acoustic beams were collinear. The assembly was mounted on a two-axis, motorized stage to enable the simultaneous acquisition of co-registered HFU and PA volumetric data. Data were collected from all five elements in receive and a synthetic-focusing algorithm was applied in post-processing to beamform the data and increase the spatial resolution and depth-of-field (DOF) of the HFU and PA images. Phantom measurements showed that the system could achieve high-resolution images (down to 90 ?m for HFU and 150 ?m for PAI) and a large DOF of >8 mm. Volume renderings of a mouse embryo showed that the scanner allowed for visualizing morphologically precise anatomy of the entire embryo along with corresponding co-registered vasculature."

According to the news reporters, the research concluded: "Major head vessels, such as the superior sagittal sinus or rostral vein, were clearly identified as well as limb bud vasculature."

For more information on this research see: High-frequency annular array with coaxial illumination for dual-modality ultrasonic and photoacoustic imaging. The Review of Scientific Instruments, 2013;84(5):053705 (see also Scientific Instruments).

Our news correspondents report that additional information may be obtained by contacting E. Filoux, Lizzi Center for Biomedical Engineering, Riverside Research, New York, New York 10038, United States. Additional authors for this research include A. Sampathkumar, P.V. Chitnis, O. Aristizabal and J.A Ketterling.

Keywords for this news article include: New York City, United States, Scientific Instruments, North and Central America.

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Source: Science Letter


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