By a News Reporter-Staff News Editor at Science Letter -- Current study results on Supramolecular Research have been published. According to news reporting originating from Hangzhou, People's Republic of China, by NewsRx correspondents, research stated, "The design of positively, charged ultrathin films for surface modification is of crucial importance for biomedical applications. Herein, we report the layer-by-layer assembly of pure positively charged ultrathin films based on the host-guest interaction of cucurbituril (CB)."
Our news editors obtained a quote from the research from Zhejiang University, "Two positively charged poly(ethylenimine)s (PEI) functionalized with guest moieties methyl viologen (MV) and indole (ID) were alternately assembled with the formation of CB ternary complex under basic conditions. The growth of the (PEI-MV@CB/PEI-ID) films was monitored by spectroscopic ellipsometry and quartz crystal microbalance. The morphology and structure of the films were characterized by scanning electron microscopy and UV-vis spectroscopy, respectively. These positively charged (PEI-MV@CB/PEI-ID) films were very stable in the pH range from 4 to 9 but disassembled immediately when subjected to a competitive guest adamantylamine."
According to the news editors, the research concluded: "Finally, the films were successfully employed as nanocontainers for DNA loading and subsequent directing the transfection of the adhered cells."
For more information on this research see: Cucurbituril Supramolecular Assembly for Positively Charged Ultrathin Films as Nanocontainers. Langmuir, 2013;29(46):14101-14107. Langmuir can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Langmuir - www.pubs.acs.org/journal/langd5)
The news editors report that additional information may be obtained by contacting D.D. Li, Zhejiang University, MOE Key Lab Macromol Synth & Functionalizat, Dept. of Polymer Sci & Engn, Hangzhou 310003, Zhejiang, People's Republic of China. Additional authors for this research include K.F. Ren, H. Chang, H.B. Wang, J.L. Wang, C.J. Chen and J. Ji (see also Supramolecular Research).
Keywords for this news article include: Asia, Hangzhou, Nanotechnology, Emerging Technologies, Supramolecular Research, Supramolecular Assemblies, People's Republic of China
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