Kytai Nguyen, a UT
"We have discovered a way to use nanoparticles to help the arteries heal themselves more effectively following one of the most common surgical procedures," said Nguyen, who joined UT
Following the angioplasty or stent, surgeons would insert the nanoparticles at the affected site, and the nanoparticles would attach themselves to the arterial wall. The nanoparticles would be programmed to recruit stem cells, which would regenerate the arterial wall's weakened cells naturally, Nguyen said.
Once cell regeneration is well under way, the nanoparticles will dissipate, she said.
The process addresses concerns that arise when a person's underlying smooth muscle cells migrate to the weakened arterial walls and the blood cells attack this damaged site.
"Your body naturally will send smooth muscle cells to the weakened walls," Nguyen said. "That creates a whole host of problems the body doesn't need. It could cause re-narrowing of an artery, leading to a heart attack."
"Using nanotechnology to solve the problem before it even occurs is ingenious," Tang said.
Nguyen previously received an
She also has teamed with a UT Southwestern colleague to develop a nanoparticle drug delivery system that will help stimulate lung growth and function after partial lung removal or destructive lung disease.
Keywords for this news article include: Surgery, Therapy, Arteries, Muscle Cells, Nanoparticle, Blood Vessels, Bioengineering, Nanotechnology, Drug Delivery Systems, Emerging Technologies,
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
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