This patent application is assigned to
The following quote was obtained by the news editors from the background information supplied by the inventors: "Stem cells are capable of being used for treatment of various medical conditions through regenerative medicine and cell therapy. Therapeutic uses of stem cells include, for example, treatment of neurological defects, such as neurological trauma (e.g. spinal cord and brain injuries) as a result of accidents or stroke, or neurological disorders such as Parkinson's disease, multiple sclerosis, Alzheimer's disease, and
"New cell therapies are rapidly being developed, and improved sources for stem cells are needed. Currently, stem cells can be obtained from umbilical cord tissue, extraction of adipose tissue, pulp from teeth, peripheral blood, and bone marrow. However, obtaining stem cells from these tissues or peripheral blood is time consuming and can require a surgical procedure and/or multiple treatments to obtain the stem cells. For example, obtaining stem cells from peripheral blood requires multiple apheresis treatments and obtaining the stem cells from bone marrow involves a painful procedure in which a large needle is inserted into the pelvis to aspirate bone marrow cells from the iliac crest.
"Another drawback to these conventional stem cell collection procedures is that therapeutically useful amounts of stem cells are not generally obtained and expansion of the stem cells is required to obtain a therapeutically useful amount of stem cells. While significant advancements have been made in the field of controlled expansion of stem cells, expanding a seed sample of stem cells into a therapeutic dosage of pluripotent or multipotent stem cells with the degree of reliability and precision necessary for therapeutic treatment has not yet been obtained. Therefore, there is a need for a method for providing therapeutically useful amounts of stem cells without expansion that is less invasive and painful to the donor, and is less costly and time consuming than currently available methods."
In addition to the background information obtained for this patent application, NewsRx journalists also obtained the inventors' summary information for this patent application: "A system and method for collecting bone marrow comprising stem cells from bone marrow exposed during a surgical procedure is disclosed. The system comprises a cannula; a collection element, such as a syringe; a storage element, such as a blood bag or blood tube; a valve assembly; and connecting tubing. The system is a closed system which significantly reduces the risk of microbial contamination during the collection and/or processing of the bone marrow. The method includes collecting bone marrow using the system during a surgical procedure, such as a hip or knee replacement surgery, and processing the collected bone marrow to obtain stem cells. Once obtained, the stem cells can be cryopreserved in a cell bank for later use.
FIGURES AND TABLES
"FIGS. 1A-1C are schematic diagrams of an exemplary embodiment of the system and method for collecting marrow stromal cells.
"FIGS. 2A and 2B are schematic diagrams of an exemplary embodiment of the system and method for collecting marrow stromal cells.
"FIGS. 3A-3D are schematic diagrams of a valve assembly according to an exemplary embodiment.
"FIG. 4 is a flow diagram of the method according to an exemplary embodiment."
URL and more information on this patent application, see: Hardy, Wayne; Singh, Vininder; Dungy, Danton S. System and Method for Collecting Stem Cells. Filed
Keywords for this news article include: Treatment, Stromal Cells,
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