News Column

Reports Outline Microbiology Study Results from UdelaR

February 18, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- A new study on Life Science Research is now available. According to news reporting originating in Montevideo, Uruguay, by NewsRx journalists, research stated, "Aqueous extracts of basidiomycete fungi were screened for the presence of lectins by hemagglutination (HA) assays with mouse, rabbit, and sheep red blood cells. From mycelia and/or fruiting bodies, 23 extracts were prepared; 15 extracts exhibited HA activity towards mouse erythrocytes, with specific activities ranging from 12 to 440 lectin units (LU)mg(-1) protein."

The news reporters obtained a quote from the research from UdelaR, "In HA inhibition assays, 43 carbohydrates including mono-, di-, tri-, tetrasaccharides, glycoproteins, and polysaccharides were tested as haptens, to determine the saccharide-binding specificities of the lectins. A novel lectin with specificity towards N-acetyl-glucosamine was purified from mycelia of Punctularia atropurpurascens using affinity chromatography on chitosan-Sepharose."

According to the news reporters, the research concluded: "The lectin has a subunit molecular mass of 67kDa determined by SDS-PAGE and a pI of 5.0."

For more information on this research see: Screening for lectins from basidiomycetes and isolation of Punctularia atropurpurascens lectin. Journal of Basic Microbiology, 2014;54(2):89-96. Journal of Basic Microbiology can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; Journal of Basic Microbiology - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-4028)

Our news correspondents report that additional information may be obtained by contacting S. Albores, UdelaR, Fac Quim, Dept. of Biociencias, Catedra Bioquim, Montevideo, Uruguay. Additional authors for this research include P. Mora, M.P. Cerdeiras and L.F. Fraguas (see also Life Science Research).

Keywords for this news article include: Uruguay, Montevideo, South America, Life Science Research

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Source: Life Science Weekly


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