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Reports Outline Biosensing Findings from Changchun Institute of Applied Chemistry

February 19, 2014



By a News Reporter-Staff News Editor at Biotech Week -- New research on Biosensing is the subject of a report. According to news originating from Changchun, People's Republic of China, by NewsRx correspondents, research stated, "The high levels of H2O2 are closely associated with cancer and progressive neurodegenerative diseases, such as Parkinson's disease. In this study, we developed a novel CuS nanoparticle-decorated reduced graphene oxide-based electrochemical biosensor for the reliable detection of H2O2."

Our news journalists obtained a quote from the research from the Changchun Institute of Applied Chemistry, "The new electrocatalyst, CuS/RGO composites was successfully prepared by heating the mixture of CuCl2 and Na2S aqueous solutions in the presence of PVP-protected graphene oxide at 180 degrees C. A potential application of CuS/RGO composite-modified electrode as a biosensor to monitor H2O2 has been investigated. The steady-state current response increases linearly with H2O2 concentration from 5 to 1500 mu M with a fast response time of less than 2 s. The detection limit (3 sigma) for determination of H2O2 has been estimated to be 0.27 mu M, which was lower than certain enzymes and noble metal nanomaterial-based biosensors. In addition, the study of storage time on the amperometric response of the sensor indicates super stability."

According to the news editors, the research concluded: "Due to these remarkable analytical advantages, the as-made sensor was applied to determine the H2O2 levels in human serum and urine samples and H2O2 released from human cervical cancer cells with satisfactory result this new nanocomposite with the high surface area and electrocatalytic activity is a promising candidate for use as an enhanced electrochemical sensing platform in the design of nonenzymatic biosensors."

For more information on this research see: A Facile One-Pot Synthesis of Copper Sulfide-Decorated Reduced Graphene Oxide Composites for Enhanced Detecting of H2O2 in Biological Environments. Analytical Chemistry, 2013;85(17):8095-8101. Analytical Chemistry can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Analytical Chemistry - www.pubs.acs.org/journal/ancham)

The news correspondents report that additional information may be obtained from J. Bai, Chinese Academy Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, People's Republic of China (see also Biosensing).

Keywords for this news article include: Asia, Changchun, Chemistry, Biosensing, Bioengineering, Electrochemical, Bionanotechnology, Nanobiotechnology, People's Republic of China

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Source: Biotech Week


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