By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Life Science Research have been presented. According to news originating from Jiangsu, People's Republic of China, by NewsRx correspondents, research stated, "A water-soluble polysaccharide (PCE-CC) was obtained from pumpkin which belongs to the family Cucubitaceae by the water and ethanol extract, organic solvent fractional extraction and deproteinization. The present study was designed to investigate PCE-CC possible mechanism underlying the improvement of damaged pancreatic islets."
Our news journalists obtained a quote from the research from the School of Food Science and Technology, "Alloxan-induced diabetic rabbits were injected with PCE-CC for 21 days to assess effects on islet tissue morphology. After 21 days, the weights of the alloxan-induced diabetic and non-diabetic rabbits fed with diet contained PCE-CC were significantly increased as compared to the negative group. The data of blood glucose (BG), total cholesterol (TC), total triglyceride (TG) and glycosylated hemoglobin (HbA1c) indicated that PCE-CC had beneficial effects on the improvement in the control of blood glucose, serum lipid and glycosylated hemoglobin levels. Observing the pancreatic tissue of the diabetic rabbits revealed that PCE-CC could promote the regeneration of damaged pancreatic islets by stimulating beta-cell proliferation, which was accompanied by a decrease in plasma glucose levels. PCE-CC was further separated and purified to obtain PCE-CCH by ion exchange and gel chromatography."
According to the news editors, the research concluded: "PCE-CCH was a heteropolysaccharide and consisted of glucose, galactose, arabinose, rhamnose and little amount of hexuronic acid, with a molecular weight of 1.15 x 10(5) Da."
For more information on this research see: Effects of polysaccharide from pumpkin on biochemical indicator and pancreatic tissue of the diabetic rabbits. International Journal of Biological Macromolecules, 2013;62():574-581. International Journal of Biological Macromolecules can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; International Journal of Biological Macromolecules - www.elsevier.com/wps/product/cws_home/525446)
The news correspondents report that additional information may be obtained from Y.J. Zhang, Southern Yangtze Univ, Sch Food Sci & Technol, Wuxi 214036, Jiangsu, People's Republic of China. Additional authors for this research include P. Chen, Y. Zhang, H. Jin, L.Y. Zhu, J. Li and H.Y. Yao (see also Life Science Research).
Keywords for this news article include: Asia, Jiangsu, Chemistry, Biochemical, Life Science Research, People's Republic of China
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