By a News Reporter-Staff News Editor at Life Science Weekly -- Fresh data on Gram-Positive Bacteria are presented in a new report. According to news reporting from Baltimore, Maryland, by NewsRx journalists, research stated, "Recent studies developed antibacterial bonding agents and composites containing a quaternary ammonium dimethacrylate (QADM) and nanoparticles of silver (NAg). The objectives of this study were to investigate: (1) the effect of antibacterial primers containing QADM and NAg on the inhibition of Streptococcus mutans impregnated into dentin blocks for the first time, and (2) the effect of QADM or NAg alone or in combination, and the effect of NAg mass fraction, on S. mutans viability in dentin."
The news correspondents obtained a quote from the research from the University of Maryland, "Scotchbond Multi-Purpose (SBMP) bonding agent was used. QADM and NAg were incorporated into SBMP primer. Six primers were tested: SBMP primer control, control+10% QADM (mass%), control+0.05% NAg, control+10% QADM+0.05% NAg, control+0.1% NAg, and control+10% QADM+0.1% NAg. S. mutans were impregnated into dentin blocks, then a primer was applied. The viable colony-forming units (CFU) were then measured by harvesting the bacteria in dentin using a sonication method. Control+10% QADM+0.1% NAg had bacteria inhibition zone 8-fold that of control (p S. mutans in dentin blocks, reducing the viable CFU in dentin by three orders of magnitude, compared to control dentin without primer. Using QADM+NAg was more effective than QADM alone. Higher NAg content increased the potency. Dentin shear bond strength was similar for all groups (p >0.1). Antibacterial primer with QADM and NAg were shown to inhibit the S. mutans impregnated into dentin blocks for the first time. Bonding agent containing QADM and NAg is promising to eradicate bacteria in tooth cavity and inhibit caries."
According to the news reporters, the research concluded: "The QADM and NAg may have applicability to other adhesives, cements, sealants and composites."
For more information on this research see: Effects of antibacterial primers with quaternary ammonium and nano-silver on Streptococcus mutans impregnated in human dentin blocks. Dental Materials, 2013;29(4):462-72. (Elsevier - www.elsevier.com; Dental Materials - www.elsevier.com/wps/product/cws_home/601024)
Our news journalists report that additional information may be obtained by contacting L. Cheng, Biomaterials & Tissue Engineering Division, Dept. of Endodontics, Prosthodontics and Operative Dentistry, University of Maryland Dental School, Baltimore, MD 21201, United States. Additional authors for this research include K. Zhang, M.D. Weir, H. Liu, X. Zhou and H.H Xu (see also Gram-Positive Bacteria).
Keywords for this news article include: Maryland, Baltimore, Chemicals, Chemistry, United States, Streptococcus, Streptococcaceae, Gram Positive Cocci, Quaternary Ammonium, Gram-Positive Bacteria, North and Central America.
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