News Column

New Nanoparticles Findings from M. Rassano et al Outlined

February 21, 2014



By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on Nanoparticles. According to news originating from Le Havre, France, by NewsRx correspondents, research stated, "Formulations incorporating different cosmetic grade TiO2 nanoparticles were developed according to a self-produced protocol on the basis of typical sunscreen cream oil-in-water emulsions. Role of nanopartides and, more specifically, the impact of two different lipophilic surface treatments on microstructure and stability of the formulations were assessed."

Our news journalists obtained a quote from the research, "Aging of formulations was performed under classical conditions at room temperature or under accelerated conditions at 50 C, with or without Ti02, and was characterized by several tools such as rheology, microscopy, and particle size measurements. Changes in emulsion stability and aggregation state of nanoparticles were followed over time. Destabilization phenomena were identified: under accelerated aging, the formulation without nanoparticles underwent a coalescence occurrence whereas the formulation incorporating nanoparticles was subjected to aggregation of the colloidal particles."

According to the news editors, the research concluded: "Besides, TiO2 nanoparticles strongly affected the particle-droplets interactions and thus modified the emulsion microstructure with a coating-dependent effect: destabilization mechanisms occur more rapidly with alumina (and) triethoxycaprylylsilane (coating 1) TiO2 nanoparticles as compared to alumina (and) isopropyl titanium triisostearate (and) triethoxycaprylylsilane crosspolymer (coating 2) nanoparticles."

For more information on this research see: Effects of aging on structure and stability of TiO2 nanoparticle-containing oil-in-water emulsions. International Journal of Pharmaceutics, 2014;461(1-2):89-96. International Journal of Pharmaceutics can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; International Journal of Pharmaceutics - www.elsevier.com/wps/product/cws_home/505513)

The news correspondents report that additional information may be obtained from M. Rassano, Univ Le Havre, LEMA, EA 3222, F-76058 Le Havre, France. Additional authors for this research include N. Hucher, C. Picard, D. Colletta, F. Le Foll and M. Grisel (see also Nanoparticles).

Keywords for this news article include: France, Europe, Le Havre, Nanotechnology, Emerging Technologies

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Source: Drug Week


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