News Column

Data from University of Bath Advance Knowledge in Drug Delivery Systems

February 19, 2014



By a News Reporter-Staff News Editor at Biotech Week -- New research on Drugs and Therapies is the subject of a report. According to news reporting originating from Bath, United Kingdom, by NewsRx correspondents, research stated, "Stimulated Raman scattering microscopy was used to assess the permeation of topically applied drugs and formulation excipients into porcine skin. This chemically selective technique generates high-resolution 3D images, from which semi-quantitative information may be elucidated."

Our news editors obtained a quote from the research from the University of Bath, "Ibuprofen, applied as a close-to-saturated solution in propylene glycol, was directly observed to crystallise in/on the skin, as the co-solvent permeated more rapidly, resulting in precipitation of the drug. Coherent Raman scattering microscopy is also an excellent tool, in conjunction with more conventional confocal fluorescence microscopy, with which to image micro/nanoparticle-based formulations."

According to the news editors, the research concluded: "Specifically, the uptake of particles into thermal ablation transport pathways in the skin has been examined."

For more information on this research see: Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies. Journal of Controlled Release, 2014;174():37-42. Journal of Controlled Release can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Journal of Controlled Release - www.elsevier.com/wps/product/cws_home/502690)

The news editors report that additional information may be obtained by contacting N.A. Belsey, University of Bath, Dept. of Chem, Bath BA2 7AY, Avon, United Kingdom. Additional authors for this research include N.L. Garrett, L.R. Contreras-Rojas, A.J. Pickup-Gerlaugh, G.J. Price, J. Moger and R.H. Guy (see also Drugs and Therapies).

Keywords for this news article include: Bath, Europe, United Kingdom, Drugs and Therapies, Drug Delivery Systems

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Source: Biotech Week


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