By a News Reporter-Staff News Editor at Physics Week -- Current study results on Nanoparticles have been published. According to news reporting originating from Beijing, People's Republic of China, by VerticalNews correspondents, research stated, "CdTe quantum dots (QDs) can provide high-intensity and photostable luminescent signals when they are used as labeling materials for sensing trace amounts of bioanalytes. However, a major concern is whether the capping ligands of CdTe QDs cause toxic effects in living systems."
Our news editors obtained a quote from the research from the Chinese Academy of Science, "In the current study, we address this problem through the complete ligand transformation of CdTe QDs from toxic thiolglycolic acid (TGA) to green citrate, which is attributed to the Cd S bond breaking and the Au-S bond formation. The highly efficient depletion of S atom from the surface of the CdTe QDs occurs after the addition of fluorosurfactant (FSN)-capped gold nanoparticles into TGA-capped CdTe QDs, accompanying with the rapid aggregation of FSN-capped gold nanoparticles via noncrosslinking mechanism in the presence of high salt. After the ligand transformation, negligible differences are observed on both photoluminescence spectra and luminescent quantum yield. In addition, the cytotoxicity of the original and new-born CdTe QDs is detected by measuring cell viability after the nanoparticle treatment. In comparison with the original TGA-capped QDs, the new-born CdTe QDs can induce minimal cytotoxicity against human hepatocellular liver carcinoma (HepG2) cells even at high dosages."
According to the news editors, the research concluded: "Our study indicates that the extremely simple method herein opens up novel pathways for the synthesis of green CdTe QDs, and the as-prepared citrate-capped CdTe QDs might have great potential for biological labeling and imaging applications."
For more information on this research see: Ligand exchange on the surface of cadmium telluride quantum dots with fluorosurfactant-capped gold nanoparticles: Synthesis, characterization and toxicity evaluation. Journal of Colloid and Interface Science, 2014;413():140-146. Journal of Colloid and Interface Science can be contacted at: Academic Press Inc Elsevier Science, 525 B St, Ste 1900, San Diego, CA 92101-4495, USA. (Elsevier - www.elsevier.com; Journal of Colloid and Interface Science - www.elsevier.com/wps/product/cws_home/622861)
The news editors report that additional information may be obtained by contacting L.Y. Wang, Chinese Academy Sci, Res Center Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, People's Republic of China. Additional authors for this research include H.X. Zhang, C. Lu and L.X. Zhao.
Keywords for this news article include: Asia, Beijing, Chemicals, Chemistry, Quantum Dots, Nanotechnology, Quantum Physics, Cadmium Telluride, Gold Nanoparticles, Transition Elements, Emerging Technologies, People's Republic of China
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