By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Nanoparticles. According to news originating from Seoul, South Korea, by NewsRx correspondents, research stated, "In order to use iron oxide nanoparticles (Fe3O4) in various applications, a surface modification that provides colloidal stability and additional functionality to the nanoparticles is necessary. For the modification of the nanoparticle surface with ligand molecules, the ligand molecule should contain an anchor group that has a strong affinity for the surface."
Our news journalists obtained a quote from the research from Seoul National University, "However, currently used anchor groups have shown some problems such as low affinity and stability as well as reactivity with the surface. In this study, arsonic acid (RAsO(OH)(2)) was investigated as a novel anchor group. It was possible to introduce azide groups on the surface of iron oxide nanoparticles using 4-azidophenylarsonic acid, and the desired functional molecules could be chemically attached to the surface via copper-catalyzed azide-alkyne cycloaddition (click chemistry). By quantifying and comparing the amount of attached anchors on the surface, it was found that arsonic acid displays better affinity than other currently used anchors (catechol, carboxylic acid). Furthermore, we examined the binding reversibility, long term anchoring stability, and anchoring stability at various pH values."
According to the news editors, the research concluded: "It was revealed that arsonic acid is a stable anchor in various conditions."
For more information on this research see: Arsonic Acid As a Robust Anchor Group for the Surface Modification of Fe3O4. Langmuir, 2013;29(48):14912-14918. Langmuir can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Langmuir - www.pubs.acs.org/journal/langd5)
The news correspondents report that additional information may be obtained from J. Ahn, Seoul National University, Dept. of Chem, Seoul 151742, South Korea. Additional authors for this research include D.S. Moon and J.K. Lee (see also Nanoparticles).
Keywords for this news article include: Asia, Seoul, South Korea, Nanotechnology, Emerging Technologies
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