By a News Reporter-Staff News Editor at Physics Week -- A new study on Nanoparticles is now available. According to news reporting originating from Hong Kong, People's Republic of China, by VerticalNews correspondents, research stated, "Fluorescent magnetic colloidal nanoparticles (FMCNPs) are produced by a two-step, seed emulsifier-free emulsion polymerization in the presence of oleic acid and sodium undecylenate-modified Fe3O4 nanoparticles (NPs). The Fe3O4/poly(St-co-GMA) nanoparticles are first synthesized as the seed and Eu(AA)(3)Phen is copolymerized with the remaining St and GMA to form the fluorescent polymer shell in the second step."
Our news editors obtained a quote from the research from the University of Hong Kong, "The uniform core-shell structured FMCNPs with a mean diameter of 120 nm exhibit superparamagnetism with saturation magnetization of 1.92 emu/g. Red luminescence from the FMCNPs is confirmed by the salient fluorescence emission peaks of europium ions at 594 and 619 nm as well as 2-photon confocal scanning laser microscopy. The in vitro cytotoxicity test conducted using the MTT assay shows good cytocompatibility and the T-2 relaxivity of the FMCNPs is 353.86 mM(-1)S(-1) suggesting its potential in magnetic resonance imaging (MRI). In vivo MRI studies based on a rat model show significantly enhanced T-2-weighted images of the liver after administration and prussian blue staining of the liver tissue slice reveals accumulation of FMCNPs in the organ."
According to the news editors, the research concluded: "The cytocompatibility, superparamagnetism, and excellent fluorescent properties of FMCNPs make them suitable for biological imaging probes in MRI and optical imaging."
For more information on this research see: Fluorescent Magnetic Fe3O4/Rare Earth Colloidal Nanoparticles for Dual-Modality Imaging. Small, 2013;9(17):2991-3000. Small can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany. (Wiley-Blackwell - www.wiley.com/; Small - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1613-6829)
The news editors report that additional information may be obtained by contacting H.E. Zhu, University of Hong Kong, Dept. of Orthopaed & Traumatol, Pokfulam, Hong Kong, People's Republic of China. Additional authors for this research include Y.L. Shang, W.H. Wang, Y.J. Zhou, P.H. Li, K. Yan, S.L. Wu, K.W.K. Yeung, Z.S. Xu, H.B. Xu and P.K. Chu.
Keywords for this news article include: Asia, Physics, Hong Kong, Nanotechnology, Superparamagnetism, Emerging Technologies, People's Republic of China
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