By a News Reporter-Staff News Editor at Biotech Week -- New research on Alkenes is the subject of a report. According to news reporting from Patras, Greece, by NewsRx journalists, research stated, "The fabrication of electrospun magnetoactive fibrous nanocomposite membranes based on the water-soluble and biocompatible poly(ethylene oxide) (PEO), the biocompatible and biodegradable poly(L-lactide) (PLLA) and preformed oleic acid-coated magnetite nanoparticles (OA.Fe3O4) is reported. Visualization of the membranes by electron microscopy techniques reveals the presence of continuous fibers of approximately 2 pm in diameter, with the magnetic nanoparticles being evenly distributed within the fibers, retaining at the same time their nanosized diameters (similar to 5 nm)."
The news correspondents obtained a quote from the research from the University of Patras, "Thermal gravimetric analysis measurements suggest that the magnetic nanoparticles embedded within the polymer fibers affect favorably the thermal stability of the membranes. Moreover, assessment of their magnetic characteristics by vibrating sample magnetometry discloses tunable superparamagnetic behavior at ambient temperature. For the first time, the biocompatibility and biodegradability of PEO/PLLA and the tunable magnetic activity of the OA.Fe3O4 are combined in the same drug delivery system, with N-acetyl-p-aminophenol (acetaminophen) as a proof-of-concept pharmaceutical. Furthermore, their heating ability under alternating current (AC) magnetic field conditions is evaluated using frequency of 110 kHz and corresponding magnetic field strength of 25 mT (19.9 kA/m)."
According to the news reporters, the research concluded: "Consequently, these magnetoactive fibrous nanocomposites exhibit promising characteristics for future exploitation in magnetothermally triggered drug delivery."
For more information on this research see: Fabrication, Characterization, and Evaluation in Drug Release Properties of Magnetoactive Poly(ethylene oxide)-Poly(L-lactide) Electrospun Membranes. Biomacromolecules, 2013;14(12):4436-4446. Biomacromolecules can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Biomacromolecules - www.pubs.acs.org/journal/bomaf6)
Our news journalists report that additional information may be obtained by contacting I. Savva, University of Patras, Dept. of Mat Sci, Patras, Greece. Additional authors for this research include A.D. Odysseos, L. Evaggelou, O. Marinica, E. Vasile, L. Vekas, Y. Sarigiannis and T. Krasia-Christoforou (see also Alkenes).
Keywords for this news article include: Patras, Greece, Europe, Alkenes, Therapy, Nanoparticle, Ethylene Oxide, Nanotechnology, Epoxy Compounds, Drug Delivery Systems, Emerging Technologies
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