The news reporters obtained a quote from the research from CSIR, "Here we report an easy synthesis of spheroidal cuprous oxide nanoparticles (CuNPs) and their organic conjugate with l-tryptophan (Trp) using surfactant, sodium dodecyl sulfate as a capping reagent. The particles looked golden yellow and showed a strong affinity to bind blood carrier proteins such as bovine serum albumin and human serum albumin. However, both optical behavior and texture of the particles altered upon conjugation with Trp. The average size of the CuNPs was estimated to be similar to 70 nm as appeared under transmission electron microscope or atomic force microscope. The biological conjugate with Trp was similar to 85 nm and looked light sky blue in aqueous suspension. The surface of the conjugated nanoparticles was smoother than the bare CuNPs. The CuNPs were found to be toxic to different cultured cancerous cells; however, conjugation with Trp attenuated the toxicity, and indicated its possible utility in developing a drug candidate for cancer in a controlled fashion."
According to the news reporters, the research concluded: "Reduced toxicity also indicated a possible use of the conjugated particle as a drug delivery system."
For more information on this research see: Copper(I) oxide nanoparticle and tryptophan as its biological conjugate: a modulation of cytotoxic effects.
Our news correspondents report that additional information may be obtained by contacting
Keywords for this news article include:
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
Most Popular Stories
- Diplomatic, Financial Fix Sought for Ukraine Crisis
- 2 Million Long-term Jobless Have No Benefits
- Las Vegas Casino Wants 'Blackout Drunk' Gambler to Pony up $500,000
- Florida Insurers Reach Out to Hispanics
- Disney Lays Off 700 From Interactive Unit
- Last Call for Hispanic Health Care Signups
- Staples Closing Stores, Moving Online
- Stocks Get Green Light on Weekly Jobless Claims
- Costco Revenue Up, Profits Down in Q2
- Where Are the World's Most Expensive Cities?