By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on DNA Research. According to news reporting from Boston, Massachusetts, by NewsRx journalists, research stated, "Nucleic acids have emerged as effective materials for assembling complex nanoscale structures. To tailor the structures to function optimally for particular applications, a broad structural design space is desired."
The news correspondents obtained a quote from the research from Dana-Farber Cancer Institute, "Despite the many discrete and extended structures demonstrated in the past few decades, the design space remains to be fully explored. In particular, the complex finite-sized structures produced to date have been typically based on a small number of structural motifs. Here, we perform a comprehensive study of the design space for complex DNA structures, using more than 30 distinct motifs derived from single-stranded tiles. These motifs self-assemble to form structures with diverse strand weaving patterns and specific geometric properties, such as curvature and twist. We performed a systematic study to control and characterize the curvature of the structures, and constructed a flat structure with a corrugated strand pattern."
According to the news reporters, the research concluded: "The work here reveals the broadness of the design space for complex DNA nanostructures."
For more information on this research see: Design Space for Complex DNA Structures. Journal of the American Chemical Society, 2013;135(48):18080-18088. Journal of the American Chemical Society can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Journal of the American Chemical Society - www.pubs.acs.org/journal/jacsat)
Our news journalists report that additional information may be obtained by contacting B. Wei, Dana Farber Canc Inst, Boston, MA 02115, United States. Additional authors for this research include M.J. Dai, C. Myhrvold, Y.G. Ke, R. Jungmann and P. Yin (see also DNA Research).
Keywords for this news article include: Boston, DNA Research, Massachusetts, United States, North and Central America
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC