By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Sulfur Amino Acids are discussed in a new report. According to news reporting from Santa Cruz, California, by NewsRx journalists, research stated, "Cysteine, as a small organic molecule and amino acid, is a basic building block for proteins and has special physiological functions in vivo. Cysteine has strong affinity for cells, which can be taken advantage for various applications."
The news correspondents obtained a quote from the research from the University of California, "A new and facile surface modification method has been developed for rare-earth doped upconversion nanoparticles (UCNs) using cysteine. Compared with unmodified samples, the water-solubility and biocompatibility of the cysteine modified NaYF4:Yb,Er and NaYF4:Yb,Tm UCNs (termed as UCN-Er-Cys and UCN-Tm-Cys, respectively) have been significantly improved, while their particle size and emission properties did not change substantially. Due to the low cytotoxicity as revealed by methyl thiazolyl tetrazolium assay, the cysteine modified UCNs were successfully applied to imaging of Hela cells in vitro and nude mouse in vivo."
According to the news reporters, the research concluded: "Most significant is that the method offers the advantages of ease of synthesis and handling as well as potentially low cost for biomedical emerging applications."
For more information on this research see: Cysteine modified rare-earth up-converting nanoparticles for in vitro and in vivo bioimaging. Biomaterials, 2014;35(1):387-392. Biomaterials can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Biomaterials - www.elsevier.com/wps/product/cws_home/30392)
Our news journalists report that additional information may be obtained by contacting Z.W. Wei, University of California, Dept. of Chem & Biochem, Santa Cruz, CA 95064, United States. Additional authors for this research include L.N. Sun, J.L. Liu, J.Z. Zhang, H.R. Yang, Y. Yang and L.Y. Shi (see also Sulfur Amino Acids).
Keywords for this news article include: Cysteine, Santa Cruz, California, Nanoparticle, United States, Nanotechnology, Sulfur Amino Acids, Neutral Amino Acids, Sulfhydryl Compounds, Emerging Technologies, North and Central America
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